Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
about
The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of actionArtemisinin-based combination therapies: a vital tool in efforts to eliminate malariaPlasmodium falciparum: multifaceted resistance to artemisininsYeast toxicogenomics: genome-wide responses to chemical stresses with impact in environmental health, pharmacology, and biotechnologyGenome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressureTreatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquineMolecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance TransporterPolyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasitesChloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification.Mass spectrometry for malaria diagnosis.Predictive computational models of substrate binding by a nucleoside transporter.Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparumOxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Quantitative genome re-sequencing defines multiple mutations conferring chloroquine resistance in rodent malariaChloroquine binding reveals flavin redox switch function of quinone reductase 2.1H-NMR metabolite profiles of different strains of Plasmodium falciparum.Differential drug efflux or accumulation does not explain variation in the chloroquine response of Plasmodium falciparum strains expressing the same isoform of mutant PfCRT.Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter.2-tert-butyl-8-quinolinamines exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization.Degrees of chloroquine resistance in Plasmodium - is the redox system involved?Novel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitroAntiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model.Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium.Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells.Genetics of chloroquine-resistant malaria: a haplotypic view.Antimalarial drugs: modes of action and mechanisms of parasite resistance.Drug-resistant malaria: molecular mechanisms and implications for public health.ABC transporters involved in drug resistance in human parasites.Novel antimalarial drug targets: hope for new antimalarial drugs.Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.Advances in quantitative structure-activity relationship models of antimalarials.Autophagy in Plasmodium, a multifunctional pathway?Plasmodium vivax trophozoites insensitive to chloroquine.Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate.Antimalarial potential of leaves of Chenopodium ambrosioides L.Accelerated denaturation of hemoglobin and the antimalarial action of chloroquine.Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.
P2860
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P2860
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@ast
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@en
type
label
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@ast
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@en
prefLabel
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@ast
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@en
P1433
P1476
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs.
@en
P2093
Coy D Fitch
P304
P356
10.1016/J.LFS.2003.10.003
P407
P577
2004-03-01T00:00:00Z