Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications.
about
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexesThe in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.Posttranscriptional silencing of VbetaDJbetaCbeta genes contributes to TCRbeta allelic exclusion in mammalian lymphocytes.The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination.Analyzing the CDR3 Repertoire with respect to TCR-Beta Chain V-D-J and V-J Rearrangements in Peripheral T Cells using HTS.Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement.Assembled DJ beta complexes influence TCR beta chain selection and peripheral V beta repertoire.
P2860
Q33865169-78709118-5806-4723-B698-2D325BF58867Q33889784-7DC24723-26F3-4E09-99D6-757224C1EF29Q34061541-F9AA49AA-647A-4DD2-8CAD-98EF3ED90B2BQ36177454-4A45440C-391B-446A-ADDC-0D5054752293Q37086903-51F78245-4156-4026-A9D3-F32AA19E111CQ42381124-590EF88C-6816-42DE-9123-E9089DD77A03Q43759402-286EF784-5F93-46BB-8407-0F6211920DEB
P2860
Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Restriction of endogenous T ce ...... signal sequence modifications.
@ast
Restriction of endogenous T ce ...... signal sequence modifications.
@en
type
label
Restriction of endogenous T ce ...... signal sequence modifications.
@ast
Restriction of endogenous T ce ...... signal sequence modifications.
@en
prefLabel
Restriction of endogenous T ce ...... signal sequence modifications.
@ast
Restriction of endogenous T ce ...... signal sequence modifications.
@en
P2093
P2860
P356
P1476
Restriction of endogenous T ce ...... signal sequence modifications.
@en
P2093
Barbara B Woodman
Craig H Bassing
Frederick W Alt
Megan Gleason
Sheila Ranganath
Tiffany M Borjeson
P2860
P304
P356
10.1073/PNAS.0700081104
P407
P577
2007-02-27T00:00:00Z