CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling.
about
Conditionally reprogrammed normal and transformed mouse mammary epithelial cells display a progenitor-cell-like phenotypeIdentifying and targeting tumor-initiating cells in the treatment of breast cancerRecognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cytokine-induced killer cells via NKG2d-ligands recognitionTransforming growth factor β as regulator of cancer stemness and metastasisA requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 miceCytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.Integrins in development and cancer.Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population.The identification and validation of Trichosstatin A as a potential inhibitor of colon tumorigenesis and colon cancer stem-like cellsAn integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.βIII-Tubulin Regulates Breast Cancer Metastases to the Brain.Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell StemnessMetformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models.Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon CancerA new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.Coalition of Oct4A and β1 integrins in facilitating metastasis in ovarian cancer.Neutrophils support lung colonization of metastasis-initiating breast cancer cellsSelective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells.Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognitionITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.Mutant p53 Amplifies Epidermal Growth Factor Receptor Family Signaling to Promote Mammary Tumorigenesis.Bioorthogonal two-component drug delivery in HER2(+) breast cancer mouse models.The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis.Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor GrowthHow integrins control breast biology.Integrin α6/Akt/Erk signaling is essential for human breast cancer resistance to radiotherapy.microRNA-mediated regulation of the tumor microenvironment.Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.Clinical applications of mouse models for breast cancer engaging HER2/neu.EZH2 expands breast stem cells through activation of NOTCH1 signaling.Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice.Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells.Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.Hyaluronic acid functional amphipathic and redox-responsive polymer particles for the co-delivery of doxorubicin and cyclopamine to eradicate breast cancer cells and cancer stem cells.c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer.Expansion of breast cancer stem cells with fibrous scaffolds.
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P2860
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@ast
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@en
type
label
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@ast
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@en
prefLabel
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@ast
CD49f and CD61 identify Her2/n ...... y the integrin-TGFβ signaling.
@en
P2093
P2860
P356
P1433
P1476
CD49f and CD61 identify Her2/n ...... by the integrin-TGFβ signaling
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.439
P407
P577
2011-09-26T00:00:00Z