BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536
about
A Cell Biologist's Field Guide to Aurora Kinase InhibitorsDrug Discovery Targeting Bromodomain-Containing Protein 4.Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET.Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Molecular Pathways: Targeting the PI3K Pathway in Cancer-BET Inhibitors to the RescueTargeting bromodomain and extraterminal proteins in breast cancer.Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites.DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
P2860
Q27308125-821370A7-B796-49CA-B1F4-5059027082D7Q30352390-262B034F-6F27-4890-A2BB-FD4810DBF0ACQ36198013-585983C1-D8CE-44DE-A14F-0339A29E068AQ38742560-203F9C63-FD31-4797-8024-B206827768F0Q38837561-6029268F-80BE-42E3-A17E-93A0CD2CF634Q38850598-73066BE2-28DE-4FB0-9B62-EA948D0ED678Q47385983-4787E773-A392-4D32-8DE4-6949D17578DEQ48355483-29CDC4AC-2E84-422C-A438-2CD6251CEE2DQ52598516-D70D8EAE-8968-4D00-A3BF-1B45352F937FQ58547215-C6A6B9BC-7A4F-42F8-9FF2-8C2801074CD9
P2860
BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@ast
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@en
type
label
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@ast
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@en
prefLabel
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@ast
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@en
P2093
P2860
P1476
BRD4 Structure-Activity Relati ...... Bromodomain Inhibitor BI-2536
@en
P2093
Jacob A Scheenstra
Jeffrey W Strovel
Jeremy L Yap
Lijia Chen
Makoto Yoshioka
Maryanna E Lanning
Rachel N Fountain
Steven Fletcher
P2860
P304
P356
10.1021/ACSMEDCHEMLETT.5B00084
P577
2015-05-18T00:00:00Z