Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting - Wikidata - wikimedia - TriplyDB

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

http://www.wikidata.org/entity/Q35697443

about

Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain Silencing disease genes in the laboratory and the clinic Chemical modification: the key to clinical application of RNA interference?Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery.Targeting hypoxia-inducible factor-1alpha with Tf-PEI-shRNA complex via transferrin receptor-mediated endocytosis inhibits melanoma growth.Aptamer-targeted cell-specific RNA interference Cationic lipid nanodisks as an siRNA delivery vehicle Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters.Gene expression and silencing for improved islet transplantation.Bipartite vectors for co-expression of a growth factor cDNA and short hairpin RNA against an apoptotic gene.Therapeutic RNA manipulation in liver disease.Significance and applications of nanoparticles in siRNA delivery for cancer therapy.Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation Inhibition of hepatitis B virus and induction of hepatoma cell apoptosis by ASGPR-directed delivery of shRNAs.Fabrication of stable and RNase-resistant RNA nanoparticles active in gearing the nanomotors for viral DNA packaging.Analysis of human protein replacement stable cell lines established using snoMEN-PR vector RNA interference for improving the outcome of islet transplantation.Co-delivery of small interfering RNA and plasmid DNA using a polymeric vector incorporating endosomolytic oligomeric sulfonamide.Targeting microRNAs in obesity.Targeted Knock-Down of miR21 Primary Transcripts Using snoMEN Vectors Induces Apoptosis in Human Cancer Cell Lines.Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group.MicroRNAs and cancer therapeutics.Development of a 2',4'-BNA/LNA-based siRNA for Dyslipidemia and Assessment of the Effects of Its Chemical Modifications In Vivo Tracking miRNAs' footprints in tumor-microenvironment interactions: Insights and implications for targeted cancer therapy.Reversible metal-dependent destabilization and stabilization of a stem-chelate-loop probe binding to an unmodified DNA target Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma Toward personalized cancer nanomedicine - past, present, and future.Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: novel options by phosphorothioate-stimulated delivery.Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.Biological barriers to therapy with antisense and siRNA oligonucleotides.Inhibition of monkeypox virus replication by RNA interference.Lipid-based nanotherapeutics for siRNA delivery siRNA applications in nanomedicine Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs.Engineering RNA for targeted siRNA delivery and medical application.Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells Integrin targeted delivery of gene therapeutics

P2860

Q24624648-E906D9FC-7EB8-40C0-A71D-1E0C929A9AE2 Q27317421-700BB1E0-A8BA-4840-9E05-D5F7A2C56594 Q29039090-CF2CE4BA-9C64-4811-B4C7-FC6B7D2832B7 Q33308712-16A75196-8B97-4E61-8207-5ECDA2ECC8DA Q33660805-0E7B81DD-2E7B-40B5-8F57-4E6144DEFC0C Q33713264-0B4D8B58-664D-4DC8-9814-0E7D52B93DC8 Q33717239-22741CAD-EA42-424F-B73D-57DD32229B51 Q33745473-21BD898B-F3BB-4E00-AB5D-B37D47115D72 Q34080079-F482B5FD-8A88-4561-BC91-769926101937 Q34102677-40E62A2B-5601-4099-8862-B86F34E40EC2 Q34144403-6464AAE5-8CB0-4F0A-AE07-0A0D6A24ADA7 Q34244756-48CBF045-80C6-4664-B697-11BA99D3372C Q34297263-9C46AE3F-01C1-45A8-9D44-25B3B3949728 Q34389283-0A8796D4-6935-47C0-A9BB-A92ADBC1DE99 Q34456173-CE98936F-2826-444A-8087-8E60ADB4AAA4 Q34520490-8241B62A-EB8A-4F90-B98F-E8C467339548 Q34701211-8AA6FA51-D663-4494-9F55-1F833C62BD75 Q34729434-76B18423-E740-418F-A9FA-70D18F0B30E3 Q34984827-C2DD3B27-C019-4624-9FE9-67712C8CF343 Q35400880-AF422E16-F747-4F5C-9036-98DF949FA414 Q35787589-96C49B9C-058C-4C8F-BE2A-1A4F19EF636E Q35823611-3BC102E5-7B70-42BB-9310-299D21FD3145 Q36116268-C4E2ED6E-94CC-4742-B708-4CAC794507F4 Q36299367-EA1DED89-E49B-4EA5-B40C-7995C7F6D284 Q36319389-FDDBC64E-3F5A-475F-926A-95A7C6491A1C Q36391384-C4388425-D26E-4BF0-A7AB-9C00B858B569 Q36411432-C7D1C2E1-B492-49E3-ABA8-DFDF314AB1CE Q36472802-159EE6A7-F977-4E68-83CE-95BA769076B0 Q36844506-72B0BA9C-E964-4D6C-A6D9-2C4420A8AFFD Q36960492-0F1C8DE0-ACBD-40E6-9A63-1CC097A04E0F Q37127281-09D8AF3E-3438-4BD3-8F21-BD9852570AD2 Q37193000-C3440621-E7A2-4794-A050-172FA3929C23 Q37378340-556907A1-3BDC-40B2-8CAC-199DC685EA02 Q37422402-1DF679C0-98AB-40F3-A48C-FF93484086C9 Q37670986-1FEE9173-0BED-4160-85DE-331EC31DFF9C Q37687965-ED8303EA-38FD-4C7A-BC15-23BB7AB54001 Q37695149-F5CB2FDB-83F0-48F5-92C6-D772F2722664 Q37709610-52F870E1-D211-4981-8D4D-3F2CC11A719C Q37841818-7C08824C-3DEF-4EB9-928E-D999D755DC86 Q37872613-E1C2C869-6CC2-406C-BBD5-77FCEE5B247A

P2860

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

http://www.wikidata.org/entity/Q35697443

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@ast

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@en

type

label

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@ast

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@en

prefLabel

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@ast

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@en

P1433

Q35697443-B40A26C1-62E5-4AF3-8352-E6C01D729B4A

P1476

Q35697443-2BCEDC4D-8DD4-4119-843D-D447F892C89E

P2093

Q35697443-083E4E27-2BEC-413A-BBEB-1FCEB48FEF2E

Q35697443-0982B024-1110-412A-9617-E5A0BFA5A403

Q35697443-F3F1637F-0AC2-48D8-AF31-5A260639BA70

P2860

Q35697443-00374887-91F9-40AC-9482-2D2A82E3FC43

Q35697443-03620D75-ADCF-4F37-A225-BABA7C5CCDB5

Q35697443-054D0608-39BD-49AC-858B-42628E81A975

Q35697443-07FDE6F4-44CE-4559-8E4A-53BF9E759EE1

Q35697443-0A57574A-2CCA-411B-AC36-67733E640844

Q35697443-0D58BFF1-29AC-48EE-BD1A-6EEB94B2363E

Q35697443-0E8E7194-161A-456A-A7C7-CA91FE6758B5

Q35697443-0ED76EF2-ADB6-45DD-A58A-9392C0A374C0

Q35697443-12854E87-6786-4E9C-AA34-6E50EBD47BAD

Q35697443-15FB66E9-E4F5-4024-84A7-011E160B17D4

P304

Q35697443-E60611CE-D920-4E07-8BCF-EEA222F3D9DE

P31

Q35697443-6A234337-4A90-485E-82F9-171FDC79EEB4

P356

Q35697443-7EA7989B-E05D-44DE-930D-361C39105494

P407

Q35697443-EF41DE2B-3610-4C4F-8A5B-084915D430F9

P433

Q35697443-96C1A3AA-28E9-4596-8425-E0EA73524AAE

P478

Q35697443-D5D3D043-B498-4BEB-BD41-A6D1B3E45D75

P577

Q35697443-3F729210-3E7B-4B66-A4B5-92C6741786C2

P5875

Q35697443-F44E84C8-0C4F-4324-A619-DB7AE886450F

P698

Q35697443-892873F2-3740-467B-A6C4-06D485A5D1A6

P921

Q35697443-A1137AC2-9712-45B6-988D-0B48E0699C15

P932

Q35697443-9E5529BA-7723-47F6-B1BD-4BB5DAE52DB2

P356

P1433

P1476

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

@en

P2093

Daniel De Paula

http://www.w3.org/2001/XMLSchema#string

M Vitória L B Bentley

http://www.w3.org/2001/XMLSchema#string

Ram I Mahato

http://www.w3.org/2001/XMLSchema#string

P2860

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.

Cleavage of the siRNA passenger strand during RISC assembly in human cells

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity

Argonaute2 is the catalytic engine of mammalian RNAi

P304

431-456

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1261/RNA.459807

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P577

2007-02-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6477939

http://www.w3.org/2001/XMLSchema#string

P698

17329355

http://www.w3.org/2001/XMLSchema#string

P921

P932

1831859

http://www.w3.org/2001/XMLSchema#string