Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.
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Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathwayNRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activationDisruption of Nrf2 synergizes with high glucose to cause heightened myocardial oxidative stress and severe cardiomyopathy in diabetic miceHemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cellsIdentification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytesTranscription factor NF-E2-related factor 1 impairs glucose metabolism in miceDifferential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cellsNegative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulumDelayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signalingMultiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivoCoordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 geneEffect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative responseVisualization of Oxidative Stress Induced by Experimental Periodontitis in Keap1-Dependent Oxidative Stress Detector-Luciferase MiceEffects of atrazine on the oxidative damage of kidney in Wister ratsA new model for raf kinase inhibitory protein induced chemotherapeutic resistanceAntioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafishOxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease.Aluminium induced endoplasmic reticulum stress mediated cell death in SH-SY5Y neuroblastoma cell line is independent of p53.Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism.NRF2, cancer and calorie restrictionCentral nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.NFE2L3 (NRF3): the Cinderella of the Cap'n'Collar transcription factors.Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training.Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levelsα-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction.KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancerThe Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence.A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.Partial inhibition of the ubiquitin-proteasome system ameliorates cardiac dysfunction following ischemia-reperfusion in the presence of high glucoseNrf2-ARE-Dependent Alterations in Zinc Transporter mRNA Expression in HepG2 Cells.Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways.Keap1 degradation by autophagy for the maintenance of redox homeostasisSubstance P Induces HO-1 Expression in RAW 264.7 Cells Promoting Switch towards M2-Like MacrophagesEmerging role of Nrf2 in protecting against hepatic and gastrointestinal disease.Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding
P2860
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P2860
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@ast
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@en
type
label
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@ast
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@en
prefLabel
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@ast
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@en
P2093
P1476
Unique function of the Nrf2-Ke ...... idant and detoxifying enzymes.
@en
P2093
Akira Kobayashi
Masayuki Yamamoto
Tsutomu Ohta
P304
P356
10.1016/S0076-6879(04)78021-0
P407
P577
2004-01-01T00:00:00Z