DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
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Noncoding RNAs in DNA repair and genome integrityThe Roles of Autophagy and the Inflammasome during Environmental Stress-Triggered Skin InflammationCisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functionsHomozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks.Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress.Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation.Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolismNuclear TRADD prevents DNA damage-mediated death by facilitating non-homologous end-joining repairPEDF and PEDF-derived peptide 44mer protect cardiomyocytes against hypoxia-induced apoptosis and necroptosis via anti-oxidative effectOxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma.DNA damage induces the accumulation of Tiam1 by blocking β-TrCP-dependent degradation.Synergistic effect of high charge and energy particle radiation and chronological age on biomarkers of oxidative stress and tissue degeneration: a ground-based study using the vertebrate laboratory model organism Oryzias latipes.Oxygen pathway modeling estimates high reactive oxygen species production above the highest permanent human habitationCell death induced by ozone and various non-thermal plasmas: therapeutic perspectives and limitations.Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulationContribution of NADPH oxidase to membrane CD38 internalization and activation in coronary arterial myocytesStimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome.Norcantharidin induced DU145 cell apoptosis through ROS-mediated mitochondrial dysfunction and energy depletionLack of gp130 expression in hepatocytes attenuates tumor progression in the DEN modelWee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence.Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells.Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents.HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer cells.Metabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytesATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB).Cytokines in radiobiological responses: a review.Up- regulation of miR-328-3p sensitizes non-small cell lung cancer to radiotherapy.A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells.Molecular mechanisms underlying chronic inflammation-associated cancers.Redox-mediated and ionizing-radiation-induced inflammatory mediators in prostate cancer development and treatment.Another facet to the anticancer response to lamellarin D: induction of cellular senescence through inhibition of topoisomerase I and intracellular Ros productionMael is essential for cancer cell survival and tumorigenesis through protection of genetic integrity.A non-linear detection of phospho-histone H2AX in EA.hy926 endothelial cells following low-dose X-irradiation is modulated by reactive oxygen species.Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria.Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cellsCYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.Structurally related hydrazone-based metal complexes with different antitumor activities variably induce apoptotic cell death.Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.mTORC1 senses stresses: Coupling stress to proteostasis.
P2860
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P2860
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@ast
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@en
type
label
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@ast
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@en
prefLabel
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@ast
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
@en
P2093
P2860
P356
P1476
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway
@en
P2093
P2860
P356
10.1038/CDDIS.2011.134
P577
2012-01-12T00:00:00Z