Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
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Activation of interferon regulatory factor 5 by site specific phosphorylationRNA sequencing reveals the role of splicing polymorphisms in regulating human gene expressionDisruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lipProcessing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right endAlternative cleavage and polyadenylation: the long and short of itInterferon-regulatory factors determine macrophage phenotype polarizationThe TLR and IL-1 signalling network at a glanceNucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and AutoinflammationAdvances in lupus geneticsRecent advances in the genetics of autoimmune diseaseIRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosusEmerging therapies for systemic lupus erythematosus--focus on targeting interferon-alphaBrief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupusGenome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lociInterferon alpha-induced lupus: proof of principleGene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositisHigh serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosusSystematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of KosraeA genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in JapaneseNetwork biology concepts in complex disease comorbiditiesGenetic mapping in human diseaseResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus.Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence DataOsteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.Association of the BANK 1 R61H variant with systemic lupus erythematosus in Americans of European and African ancestry.Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosusSurvival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data.Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populationsPathogenesis of human systemic lupus erythematosus: recent advances.The lupus family registry and repository.Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patientsCritical role of IRF-5 in regulation of B-cell differentiation.Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study.Interferon-alpha: a therapeutic target in systemic lupus erythematosusGenetic factors predisposing to systemic lupus erythematosus and lupus nephritis.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus
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P2860
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Three functional variants of I ...... ve haplotypes for human lupus.
@ast
Three functional variants of I ...... ve haplotypes for human lupus.
@en
type
label
Three functional variants of I ...... ve haplotypes for human lupus.
@ast
Three functional variants of I ...... ve haplotypes for human lupus.
@en
prefLabel
Three functional variants of I ...... ve haplotypes for human lupus.
@ast
Three functional variants of I ...... ve haplotypes for human lupus.
@en
P2093
P2860
P50
P356
P1476
Three functional variants of I ...... ve haplotypes for human lupus.
@en
P2093
Chieko Kyogoku
Clarence Gillett
Deborah S Cunninghame Graham
Emily C Baechler
Geoffrey Hom
Gunnel Nordmark
Irina A Vlasova
Iva Gunnarsson
Jason W Bauer
Kathy Moser
P2860
P304
P356
10.1073/PNAS.0701266104
P407
P50
P577
2007-04-05T00:00:00Z