The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study.
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Towards a Molecular Understanding of the Link between Imatinib Resistance and Kinase Conformational DynamicsInsight on Mutation-Induced Resistance from Molecular Dynamics Simulations of the Native and Mutated CSF-1R and KITA place for precision medicine in bladder cancer: targeting the FGFRs.Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.Blowing a breath of fresh share on data.Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.Design, synthesis, and biological evaluation of 3-vinyl-quinoxalin-2(1H)-one derivatives as novel antitumor inhibitors of FGFR1.Rapid and Reliable Binding Affinity Prediction of Bromodomain Inhibitors: A Computational Study.Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophilaInsight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study.Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.Biophysical characterization of drug-resistant mutants of fibroblast growth factor receptor 1.NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074.
P2860
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P2860
The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@ast
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en-gb
type
label
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@ast
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en-gb
prefLabel
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@ast
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en-gb
P2093
P2860
P1154
2-s2.0-84928731157
P1433
P1476
The Effect of Mutations on Dru ...... imental and Theoretical Study.
@en
P2093
Ludovico Sutto
Matilda Katan
Nethaji Thiyagarajan
Paul Ashford
Peter V Coveney
Sarah V Williams
Shunzhou Wan
Tom D Bunney
P2860
P304
P356
10.1016/J.EBIOM.2015.02.009
P5530
P577
2015-03-01T00:00:00Z
P5875
P6179
1031921802