A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.
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Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolismMucolipin co-deficiency causes accelerated endolysosomal vacuolation of enterocytes and failure-to-thrive from birth to weaningMolecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibitionTransgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural geneSuperior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: an investigation of apobec-1 knock-out and wild-type micePostprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oilPhosphorylation of Sar1b protein releases liver fatty acid-binding protein from multiprotein complex in intestinal cytosol enabling it to bind to endoplasmic reticulum (ER) and bud the pre-chylomicron transport vesicleIdentification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestineThe biogenesis of chylomicronsNocturnin regulates circadian trafficking of dietary lipid in intestinal enterocytes.Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDLAnalysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.Analysis of organ physiology in transgenic mice.Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) studyAn apolipoprotein B100 mimotope prevents obesity in mice.New insights into the molecular mechanism of intestinal fatty acid absorption.Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes.Metabolic adaptations to dietary fat malabsorption in chylomicron-deficient mice.Numerous transcriptional alterations in liver persist after short-term enzyme-replacement therapy in a murine model of mucopolysaccharidosis type VII.Lipoprotein secretion and triglyceride stores in the heart.Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte.Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies.Multiple, independently regulated pathways of cholesterol transport across the intestinal epithelial cells.An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis.Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer element is located betweeHuman apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis.Critical roles for α/β hydrolase domain 5 (ABHD5)/comparative gene identification-58 (CGI-58) at the lipid droplet interface and beyond.Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat.Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis.The Impact of Egg Nutrient Composition and Its Consumption on Cholesterol Homeostasis
P2860
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P2860
A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
A genetic model for absent chy ...... ver, but not in the intestine.
@ast
A genetic model for absent chy ...... ver, but not in the intestine.
@en
type
label
A genetic model for absent chy ...... ver, but not in the intestine.
@ast
A genetic model for absent chy ...... ver, but not in the intestine.
@en
prefLabel
A genetic model for absent chy ...... ver, but not in the intestine.
@ast
A genetic model for absent chy ...... ver, but not in the intestine.
@en
P2093
P2860
P356
P1476
A genetic model for absent chy ...... iver, but not in the intestine
@en
P2093
A Connolly
R L Hamilton
R V Farese
P2860
P304
P356
10.1172/JCI118365
P407
P577
1995-12-01T00:00:00Z