Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.
about
Apc mutation enhances PyMT-induced mammary tumorigenesisActin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary glandYES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cellsSrc Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer.LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasisC-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment responseCombined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression.c-Src drives intestinal regeneration and transformation.Oncolytic virotherapy for ovarian cancer.Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.Progress in breast cancer research.Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal TransitionFocal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivoInducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression.Connexin43 cardiac gap junction remodeling: lessons from genetically engineered murine models.Pharmacology of Src family kinases and therapeutic implications of their modulators.Integrin signalling regulates YAP and TAZ to control skin homeostasis.HER2 drives Mucin-like 1 to control proliferation in breast cancer cells.Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.A deuterated analog of dasatinib disrupts cell cycle progression and displays anti-non-small cell lung cancer activity in vitro and in vivo.Integrin signaling in mammary epithelial cells and breast cancer.c-Src regulates cell cycle proteins expression through protein kinase B/glycogen synthase kinase 3 beta and extracellular signal-regulated kinases 1/2 pathways in MCF-7 cells.SRC increases MYC mRNA expression in ER+ breast cancer via mRNA stabilization and inhibition of p53 function.Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.c-Src regulates cargo transit via the Golgi in pancreatic acinar cells
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P2860
Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mammary epithelial-specific di ...... progression and tumorigenesis.
@ast
Mammary epithelial-specific di ...... progression and tumorigenesis.
@en
type
label
Mammary epithelial-specific di ...... progression and tumorigenesis.
@ast
Mammary epithelial-specific di ...... progression and tumorigenesis.
@en
prefLabel
Mammary epithelial-specific di ...... progression and tumorigenesis.
@ast
Mammary epithelial-specific di ...... progression and tumorigenesis.
@en
P2093
P2860
P356
P1476
Mammary epithelial-specific di ...... progression and tumorigenesis.
@en
P2093
Harvey W Smith
Richard Marcotte
Rosalie V McDonough
Virginie Sanguin-Gendreau
William J Muller
P2860
P304
P356
10.1073/PNAS.1018861108
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P577
2011-05-31T00:00:00Z