Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. - Wikidata - wikimedia - TriplyDB

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.

http://www.wikidata.org/entity/Q35794043

about

Regenerating proteins and their expression, regulation, and signaling The NF-κB subunit RelA/p65 is dispensable for successful liver regeneration after partial hepatectomy in mice A small molecule inhibitor of NFκB blocks ER stress and the NLRP3 inflammasome and prevents progression of pancreatitis.In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging.Autophagy in alcohol-induced multiorgan injury: mechanisms and potential therapeutic targets Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.Regeneration and repair of the exocrine pancreas.Dicer regulates differentiation and viability during mouse pancreatic cancer initiation Cutting edge: NF-κB p65 and c-Rel control epidermal development and immune homeostasis in the skin Earliest innate immune responses require macrophage RelA during pneumococcal pneumonia.Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice Interaction between NFκB and NFAT coordinates cardiac hypertrophy and pathological remodeling.NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation.Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles.Type I alveolar epithelial cells mount innate immune responses during pneumococcal pneumonia.The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis.IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice.N-terminal cleaved pancreatitis-associated protein-III (PAP-III) serves as a scaffold for neurites and promotes neurite outgrowth.Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.Roles of STAT3 in protein secretion pathways during the acute-phase response.A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer.Pancreatic acinar cell nuclear factor κB activation because of bile acid exposure is dependent on calcineurin.Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis.Infusion of Bone Marrow Mesenchymal Stem Cells Attenuates Experimental Severe Acute Pancreatitis in Rats.Network analysis reveals functional cross-links between disease and inflammation genes.Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice.Roles of lung epithelium in neutrophil recruitment during pneumococcal pneumonia New insights into the pathogenesis of pancreatitis.Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation.OGT-mediated O-GlcNAcylation promotes NF-κB activation and inflammation in acute pancreatitis.MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells.GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.

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P2860

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.

http://www.wikidata.org/entity/Q35794043

description

2007 nî lūn-bûn

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Pancreas-specific RelA/p65 tru ...... llowing cerulein pancreatitis.

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Pancreas-specific RelA/p65 tru ...... llowing cerulein pancreatitis.

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Pancreas-specific RelA/p65 tru ...... llowing cerulein pancreatitis.

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Pancreas-specific RelA/p65 tru ...... llowing cerulein pancreatitis.

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Pancreas-specific RelA/p65 tru ...... llowing cerulein pancreatitis.

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Alexander Pfeifer

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Dieter Saur

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Fabian Geisler

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Hassan Nakhai

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Marina Lesina

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Matthias Treiber

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Roland M Schmid

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Stephan Paxian

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P2860

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

Generalized lacZ expression with the ROSA26 Cre reporter strain

Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis

Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I

Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice

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1490-1501

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10.1172/JCI29882

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6

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117

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Aizkuņģa dziedzeris

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1868784

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