A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.
about
GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodiesCytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathwayEndothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodiesA role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesionInterleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cellsPlatelet CD62 expression and PDGFAB secretion in patients undergoing PTCA and treatment with abciximabIncreased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritisLeukocyte adhesion molecules in animal models of inflammatory bowel diseaseAccumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin.Effects of oxygen-induced lung damage on megakaryocytopoiesis and platelet homeostasis in a rat model.2-Arachidonoylglycerol enhances platelet formation from human megakaryoblasts.Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing.Thrombus imaging in a primate model with antibodies specific for an external membrane protein of activated plateletsDownregulation of human platelet reactivity by neutrophils. Participation of lipoxygenase derivatives and adhesive proteins.Gray platelet syndrome. Dissociation between abnormal sorting in megakaryocyte alpha-granules and normal sorting in Weibel-Palade bodies of endothelial cells.Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectinP-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancerDivergent fates of P- and E-selectins after their expression on the plasma membrane.A reliable plasma marker of platelet activation: does it exist?Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.Historical perspective and future directions in platelet research.Evaluation of Random Donor Platelets Produced from Buffy Coat Stored for 24 h at Ambient Temperature: Should This be Implemented in India?Gray platelet syndrome. Demonstration of alpha granule membranes that can fuse with the cell surface.P-selectin induces the expression of tissue factor on monocytes.Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation.Role of endothelial selectins in wound repair.Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types.Decreased content and surface expression of alpha-granule membrane protein GMP-140 in one of two types of platelet alpha delta storage pool deficiency.The effect of upstream platelet-fibrinogen interactions on downstream adhesion and activation.SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane.Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets.Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin.The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actininRole of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.Peritoneal macrophages express both P-selectin and PSGL-1.Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migrationMegakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice.GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interactionThe selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.
P2860
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P2860
A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
A platelet alpha granule membr ...... ule-external membrane protein.
@ast
A platelet alpha granule membr ...... ule-external membrane protein.
@en
type
label
A platelet alpha granule membr ...... ule-external membrane protein.
@ast
A platelet alpha granule membr ...... ule-external membrane protein.
@en
prefLabel
A platelet alpha granule membr ...... ule-external membrane protein.
@ast
A platelet alpha granule membr ...... ule-external membrane protein.
@en
P2093
P2860
P356
P1476
A platelet alpha granule membr ...... ule-external membrane protein.
@en
P2093
C L Berman
J D Wencel-Drake
M H Ginsberg
P2860
P304
P356
10.1172/JCI112542
P407
P577
1986-07-01T00:00:00Z