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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

http://www.wikidata.org/entity/Q35812701

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Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer Targeting androgen receptor in estrogen receptor-negative breast cancer ConceptGen: a gene set enrichment and gene set relation mapping tool Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review Role of the TMPRSS2-ERG gene fusion in prostate cancer Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype CD24 is an effector of HIF-1-driven primary tumor growth and metastasis.Neoplasia: the second decade.REGNET: mining context-specific human transcription networks using composite genomic information.Pathway analysis reveals functional convergence of gene expression profiles in breast cancer Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup.Exploring clinical associations using '-omics' based enrichment analyses.Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases Knowledge-based data analysis comes of age.Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis.Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy NF-κB activation-induced anti-apoptosis renders HER2-positive cells drug resistant and accelerates tumor growth.Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer.MYC regulation of a "poor-prognosis" metastatic cancer cell state.Enrichment map: a network-based method for gene-set enrichment visualization and interpretation.Large-scale analysis of expression signatures reveals hidden links among diverse cellular processes.Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer.Integrated analysis identifies interaction patterns between small molecules and pathways Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy SIGNATURE: a workbench for gene expression signature analysis.Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures.Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage Multi-edge gene set networks reveal novel insights into global relationships between biological themes.Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.Oncogenic gene fusions in epithelial carcinomas An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Breast cancer methylomes establish an epigenomic foundation for metastasis.A pharmacogenomic method for individualized prediction of drug sensitivity Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis.Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

http://www.wikidata.org/entity/Q35812701

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2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Molecular concepts analysis links tumors, pathways, mechanisms, and drugs

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Arul M Chinnaiyan

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Daniel R Rhodes

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Debashis Ghosh

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Nicole Kasper

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Radhika Varambally

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Scott A Tomlins

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Sooryanarayana Varambally

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Terrence R Barrette

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Vasudeva Mahavisno

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P2860

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

InterPro, progress and status in 2005

L2L: a simple tool for discovering the hidden significance in microarray expression data

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma.

Combinatorial microRNA target predictions

The KEGG resource for deciphering the genome

A gene-expression signature as a predictor of survival in breast cancer

The Gene Ontology (GO) database and informatics resource

8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas

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443-454

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10.1593/NEO.07292

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5

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9

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Shanker Kalyana-Sundaram

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2007-05-01T00:00:00Z

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6302382

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17534450

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1877973

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