Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis - Wikidata - wikimedia - TriplyDB

Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

http://www.wikidata.org/entity/Q35814233

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Genome Editing in C. elegans and Other Nematode Species DNA polymerase θ (POLQ), double-strand break repair, and cancer Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?SapTrap, a Toolkit for High-Throughput CRISPR/Cas9 Gene Modification in Caenorhabditis elegans High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes.Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.Linking DNA polymerase theta structure and function in health and disease CRISPR-Based Methods for Caenorhabditis elegans Genome Engineering.Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion.Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9 A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.Improved assembly of noisy long reads by k-mer validation Optogenetic mutagenesis in Caenorhabditis elegans.Targeted genome editing in Caenorhabditis elegans using CRISPR/Cas9.A maternal-effect selfish genetic element in Caenorhabditis elegans.Targeted mutagenesis in a human-parasitic nematode.Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks.Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.The DNA translocase RAD5A acts independently of the other main DNA repair pathways, and requires both its ATPase and RING domain for activity in Arabidopsis thaliana.

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

http://www.wikidata.org/entity/Q35814233

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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type

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

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Nature Communications

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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis

@en

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Marcel Tijsterman

http://www.w3.org/2001/XMLSchema#string

Robin van Schendel

http://www.w3.org/2001/XMLSchema#string

Sophie F Roerink

http://www.w3.org/2001/XMLSchema#string

Vincent Portegijs

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Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

The genetics of Caenorhabditis elegans

High-efficiency bypass of DNA damage by human DNA polymerase Q

RNA-guided human genome engineering via Cas9

Efficient genome editing in zebrafish using a CRISPR-Cas system

Fast and accurate short read alignment with Burrows-Wheeler transform

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

PLINK: a tool set for whole-genome association and population-based linkage analyses

Biochemical evidence for Ku-independent backup pathways of NHEJ

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7394

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scholarly article

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10.1038/NCOMMS8394

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6

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Sander van den Heuvel

Vincent Portegijs

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2015-06-16T00:00:00Z

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278732634

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1053547181

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26077599

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4490562

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