The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development.
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Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15Regulating the immune system via IL-15 transpresentationInsights into cytokine-receptor interactions from cytokine engineeringThe importance of regulatory T-cell heterogeneity in maintaining self-toleranceIL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa.IL-15 receptor α signaling constrains the development of IL-17-producing γδ T cells.Stable inhibitory activity of regulatory T cells requires the transcription factor HeliosTransient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8+ T effector-memory cells.Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Rα Dependent.Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapyInflammatory Signals Regulate IL-15 in Response to Lymphodepletion.IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas.IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cellsEnhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulationFunctions of IL-15 in anti-viral immunity: multiplicity and variety.Promoting Immune Regulation in Type 1 Diabetes Using Low-Dose Interleukin-2.Evolution of Cytokine Receptor Signaling.The Distribution of Human Stem Cell-like Memory T Cell in Lung Cancer.Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex.Visualization of granzyme B-expressing CD8 T cells during primary and secondary immune responses to Listeria monocytogenes.The ERM Protein Moesin Regulates CD8(+) Regulatory T Cell Homeostasis and Self-Tolerance.MicroRNA regulation in human CD8+ T cell subsets--cytokine exposure alone drives miR-146a expression.Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD mice.Low CD25 on autoreactive Tregs impairs tolerance via low dose IL-2 and antigen delivery.Out-sourcing for Trans-presentation: Assessing T Cell Intrinsic and Extrinsic IL-15 Expression with Il15 Gene Reporter Mice.Novel adjuvant for immunization against tuberculosis: DNA vaccine expressing Mycobacterium tuberculosis antigen 85A and interleukin-15 fusion product elicits strong immune responses in mice.HSV-Induced Systemic Inflammation as an Animal Model for Behçet's Disease and Therapeutic Applications
P2860
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P2860
The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The basis of distinctive IL-2- ...... ector-memory cell development.
@ast
The basis of distinctive IL-2- ...... ector-memory cell development.
@en
type
label
The basis of distinctive IL-2- ...... ector-memory cell development.
@ast
The basis of distinctive IL-2- ...... ector-memory cell development.
@en
prefLabel
The basis of distinctive IL-2- ...... ector-memory cell development.
@ast
The basis of distinctive IL-2- ...... ector-memory cell development.
@en
P2093
P2860
P356
P1476
The basis of distinctive IL-2- ...... ector-memory cell development.
@en
P2093
Iris Castro
Michael J Dee
Thomas R Malek
P2860
P304
P356
10.4049/JIMMUNOL.1003961
P407
P577
2011-10-07T00:00:00Z