A T cell receptor-specific blockade of positive selection.
about
CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapseLow ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation.Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection.Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptideAltered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection.Genomics-based identification of self-ligands with T cell receptor-specific biological activity.Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact.Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia.Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex.Functional development of the T cell receptor for antigenEfficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment.An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181aMolecular and genetic parameters defining T-cell clonal selection.
P2860
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P2860
A T cell receptor-specific blockade of positive selection.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A T cell receptor-specific blockade of positive selection.
@ast
A T cell receptor-specific blockade of positive selection.
@en
type
label
A T cell receptor-specific blockade of positive selection.
@ast
A T cell receptor-specific blockade of positive selection.
@en
prefLabel
A T cell receptor-specific blockade of positive selection.
@ast
A T cell receptor-specific blockade of positive selection.
@en
P2093
P2860
P356
P1476
A T cell receptor-specific blockade of positive selection.
@en
P2093
P2860
P356
10.1084/JEM.189.1.13
P407
P577
1999-01-01T00:00:00Z