Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice
about
Stage-specific changes in fetal thymocyte proliferation during the CD4-8- to CD4+8+ transition in wild type, Rag1-/-, and Hoxa3,Pax1 mutant mice.Identification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularityToxicity of staphylococcal enterotoxins potentiated by lipopolysaccharide: major histocompatibility complex class II molecule dependency and cytokine release.Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity.Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD miceFunctional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.Purified hematopoietic stem cell grafts induce tolerance to alloantigens and can mediate positive and negative T cell selectionClass I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cellsYoung, proliferative thymic epithelial cells engraft and function in aging thymuses.A T cell receptor-specific blockade of positive selection.Immune CD4+ T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epitheliumEvidence for a single-niche model of positive selection.Human adaptive immune system Rag2-/-gamma(c)-/- mice.Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene.The final maturation of at least some single-positive CD4(hi) thymocytes does not require T cell receptor-major histocompatibility complex contactQuantitative impact of thymic clonal deletion on the T cell repertoire.Selection of antigen-specific T cells by a single IEk peptide combinationNegative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populationsMurine AIDS is an antigen-driven disease: requirements for major histocompatibility complex class II expression and CD4+ T cellsFibroblasts can induce thymocyte positive selection in vivoDendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.MHC class II antigen presentation and immunological abnormalities due to deficiency of MHC class II and its associated genes.Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoireAge-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defectsPrevention of type 1 diabetes by gene therapy.CD4 T cells and major histocompatibility complex class II expression influence worm expulsion and increased intestinal muscle contraction during Trichinella spiralis infection.Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells.Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells.Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo.Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures.Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro.A humanized mouse model of anaphylactic peanut allergy.
P2860
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P2860
Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Class II-positive hematopoieti ...... tes in class II-deficient mice
@ast
Class II-positive hematopoieti ...... tes in class II-deficient mice
@en
type
label
Class II-positive hematopoieti ...... tes in class II-deficient mice
@ast
Class II-positive hematopoieti ...... tes in class II-deficient mice
@en
prefLabel
Class II-positive hematopoieti ...... tes in class II-deficient mice
@ast
Class II-positive hematopoieti ...... tes in class II-deficient mice
@en
P2093
P2860
P356
P1476
Class II-positive hematopoieti ...... tes in class II-deficient mice
@en
P2093
H Auchincloss
J S Markowitz
L H Glimcher
M J Grusby
P2860
P304
P356
10.1073/PNAS.90.7.2779
P407
P577
1993-04-01T00:00:00Z