Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants. - Wikidata - wikimedia - TriplyDB

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

http://www.wikidata.org/entity/Q35836140

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Vaccine adjuvants as potential cancer immunotherapeutics Improving the clinical impact of biomaterials in cancer immunotherapy.Possible functions of CD169-positive sinus macrophages in lymph nodes in anti-tumor immune responses Biodegradable Polymeric Nanoparticles-Based Vaccine Adjuvants for Lymph Nodes Targeting Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?Synthetic Nanoparticles for Vaccines and Immunotherapy Engineering New Approaches to Cancer Vaccines Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation.Combinatorial Delivery of Dual and Triple TLR Agonists via Polymeric Pathogen-like Particles Synergistically Enhances Innate and Adaptive Immune Responses.Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity Beyond antigens and adjuvants: formulating future vaccines.Targeted Programming of the Lymph Node Environment Causes Evolution of Local and Systemic Immunity Vaccine nanoparticles for protection against HIV infection.Treatment of chronic hepatitis B with pattern recognition receptor agonists: Current status and potential for a cure Engineering immunity: Modulating dendritic cell subsets and lymph node response to direct immune-polarization and vaccine efficacy.Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway.Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook.Biomaterials for enhancing anti-cancer immunity.Self-assembling peptide-based building blocks in medical applications.Strategies for designing synthetic immune agonists.The role of myeloid cells in cancer therapies.Delivering safer immunotherapies for cancer.Turbocharging vaccines: emerging adjuvants for dendritic cell based therapeutic cancer vaccines.Biologics to treat substance use disorders: Current status and new directions Synthetic nanovaccines for immunotherapy.Synthesis of Lymph Node-Targeting Adjuvants.Herpesvirus-Associated Lymphadenitis Distorts Fibroblastic Reticular Cell Microarchitecture and Attenuates CD8 T Cell Responses to Neurotropic Infection in Mice Lacking the STING-IFNα/β Defense Pathways.A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists.Nanodiamond enhances immune responses in mice against recombinant HA/H7N9 protein.Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors.Rethinking cancer nanotheranostics.TNF-receptor superfamily agonists as molecular adjuvants for cancer vaccines.IRF3 and type I interferons fuel a fatal response to myocardial infarction.An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells.Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization.A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.Control of autoimmune inflammation using liposomes to deliver positive allosteric modulators of metabotropic glutamate receptors.cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses.

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P2860

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

http://www.wikidata.org/entity/Q35836140

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

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Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

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type

label

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

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Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

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prefLabel

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

@ast

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

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Journal of Clinical Investigation

P1476

Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants

@en

P2093

Darrell J Irvine

http://www.w3.org/2001/XMLSchema#string

Gregory L Szeto

http://www.w3.org/2001/XMLSchema#string

Monica P Crespo

http://www.w3.org/2001/XMLSchema#string

Stefanie Mueller

http://www.w3.org/2001/XMLSchema#string

Stephanie H Chen

http://www.w3.org/2001/XMLSchema#string

Wuhbet Abraham

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P2860

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system

STING is a direct innate immune sensor of cyclic di-GMP

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

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2532-2546

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10.1172/JCI79915

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6

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125

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Melissa C Hanson

Kelly D Moynihan

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2015-05-04T00:00:00Z

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25938786

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4497758

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