Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
about
Radioresistance of Brain TumorsPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsBrain tumor stem cells: Molecular characteristics and their impact on therapyNovel delivery strategies for glioblastomaTargeting glioma stem cells: a novel framework for brain tumorsEvaluation of tyrosine kinase inhibitor combinations for glioblastoma therapyA kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastomaCannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effectTargeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.Targeting A20 decreases glioma stem cell survival and tumor growth.Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.Molecular targeting of glioblastoma: Drug discovery and therapiesPotential therapeutic implications of cancer stem cells in glioblastomaCD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway.The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patientsA novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells.Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells.PTEN reconstitution alters glioma responses to c-Met pathway inhibition.Radiosensitization of Primary Human Glioblastoma Stem-like Cells with Low-Dose AKT Inhibition.Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-κB signaling pathway in human pancreatic ductal adenocarcinoma.Emerging insights into the molecular and cellular basis of glioblastoma.Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status.Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells.Identification of survival genes in human glioblastoma cells by small interfering RNA screening.p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.Understanding the role of tumor stem cells in glioblastoma multiforme: a review article.Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting.Glioblastoma stem cells.Evi1 forms a bridge between the epigenetic machinery and signaling pathways.Glioma stem cell maintenance: the role of the microenvironment.Characteristic features of stem cells in glioblastomas: from cellular biology to genetics.Therapeutic targeting of EGFR-activated metabolic pathways in glioblastoma.The emerging role of the phosphatidylinositol 3-kinase/ akt/mammalian target of rapamycin signaling network in cancer stem cell biology.Role of Akt in human malignant glioma: from oncogenesis to tumor aggressiveness.Glioblastoma stem cells: Molecular characteristics and therapeutic implicationsRecent advances in targeted therapy for glioblastoma.Neurotrophin signaling in cancer stem cells.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy.
P2860
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P2860
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@ast
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@en
type
label
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@ast
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@en
prefLabel
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@ast
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@en
P2093
P2860
P1476
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells.
@en
P2093
Angelo L Vescovi
Betty M Tyler
Christine L Hann
Gary L Gallia
Gregory J Riggins
Henry Brem
Vincent L Giranda
P2860
P304
P356
10.1158/1535-7163.MCT-08-0680
P577
2009-02-10T00:00:00Z