Emerging insights into the molecular and cellular basis of glioblastoma. - Wikidata - wikimedia - TriplyDB

Emerging insights into the molecular and cellular basis of glioblastoma.

Emerging insights into the molecular and cellular basis of glioblastoma.

http://www.wikidata.org/entity/Q35914897

about

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy New perspectives in glioblastoma antiangiogenic therapy Development of targeted therapies in treatment of glioblastoma Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date Role of SOX family of transcription factors in central nervous system tumors Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma Contemporary murine models in preclinical astrocytoma drug development Asymmetric Distribution of GFAP in Glioma Multipotent Cells The somatic genomic landscape of glioblastoma Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1.Functional imaging in adult and paediatric brain tumours.Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma CSNK1A1 and Gli2 as Novel Targets Identified Through an Integrative Analysis of Gene Expression Data, Protein-Protein Interaction and Pathways Networks in Glioblastoma Tumors: Can These Two Be Antagonistic Proteins?Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres.The Transcription Regulator Krüppel-Like Factor 4 and Its Dual Roles of Oncogene in Glioblastoma and Tumor Suppressor in Neuroblastoma.Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas.Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro.EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.Survivin transcript variant 2 drives angiogenesis and malignant progression in proneural gliomas.Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.MiR-181b sensitizes glioma cells to teniposide by targeting MDM2.Medical therapy of gliomas.OSU-03012 interacts with lapatinib to kill brain cancer cells Current status of gene therapy for brain tumors.mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.Conditional astroglial Rictor overexpression induces malignant glioma in mice Response to imatinib as a function of target kinase expression in recurrent glioblastoma.Collateral Lethality: A new therapeutic strategy in oncology TRIM28 and β-actin identified via nanobody-based reverse proteomics approach as possible human glioblastoma biomarkers Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.

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P2860

Emerging insights into the molecular and cellular basis of glioblastoma.

http://www.wikidata.org/entity/Q35914897

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name

Emerging insights into the molecular and cellular basis of glioblastoma.

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Genes & Development

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Emerging insights into the molecular and cellular basis of glioblastoma.

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Alan Wang

http://www.w3.org/2001/XMLSchema#string

Benito Campos

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Gavin P Dunn

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Giannicola Genovese

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Ian F Dunn

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Jill Wykosky

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Keith L Ligon

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Mikael L Rinne

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Milan G Chheda

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Pankaj K Agarwalla

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P2860

Profiling critical cancer gene mutations in clinical tumor samples

Yes and PI3K bind CD95 to signal invasion of glioblastoma

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

PKC-ι promotes glioblastoma cell survival by phosphorylating and inhibiting BAD through a phosphatidylinositol 3-kinase pathway

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation

Cancerous stem cells can arise from pediatric brain tumors

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756-784

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10.1101/GAD.187922.112

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8

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26

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Cameron Brennan

Frank B Furnari

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2012-04-01T00:00:00Z

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224052650

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3337451

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