Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging
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Advancing biomedical imagingNanosized contrast agents to noninvasively detect kidney inflammation by magnetic resonance imagingBioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse modelThe unique neonatal NK cells: a critical component required for neonatal autoimmune disease induction by maternal autoantibodyIdentification of Orch3, a locus controlling dominant resistance to autoimmune orchitis, as kinesin family member 1CGLP-1R-targeting magnetic nanoparticles for pancreatic islet imaging.Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cellsNardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.The kinetics of plasmacytoid dendritic cell accumulation in the pancreas of the NOD mouse during the early phases of insulitis.Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouseEpigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.Antigen recognition in the islets changes with progression of autoimmune islet infiltration.Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice.Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients.Rapid, high efficiency isolation of pancreatic ß-cells.Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes.DCIR2+ cDC2 DCs and Zbtb32 Restore CD4+ T-Cell Tolerance and Inhibit DiabetesAdoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD miceAnti-serpin antibody-mediated regulation of proteases in autoimmune diabetesManaging diabetes with nanomedicine: challenges and opportunitiesType 1 diabetes genetic susceptibility and dendritic cell function: potential targets for treatment.Limitations of IL-2 and rapamycin in immunotherapy of type 1 diabetesInsulinoma-released exosomes activate autoreactive marginal zone-like B cells that expand endogenously in prediabetic NOD mice.Transcription factor IRF8 controls Th1-like regulatory T-cell functionCD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.Peripheral tolerance and autoimmunity: lessons from in vivo imaging.The role of the complement system in metabolic organs and metabolic diseases.A Mathematical Model of T1D Acceleration and Delay by Viral Infection.RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm.PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.Long-term bisphenol A exposure accelerates insulitis development in diabetes-prone NOD mice.Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors.VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells.Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice.Imaging dynamics of CD11c⁺ cells and Foxp3⁺ cells in progressive autoimmune insulitis in the NOD mouse model of type 1 diabetes.The regulation of immune tolerance by FOXP3.CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms.Imaging the emergence and natural progression of spontaneous autoimmune diabetes.
P2860
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P2860
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Early window of diabetes deter ...... ntified by noninvasive imaging
@ast
Early window of diabetes deter ...... ntified by noninvasive imaging
@en
type
label
Early window of diabetes deter ...... ntified by noninvasive imaging
@ast
Early window of diabetes deter ...... ntified by noninvasive imaging
@en
prefLabel
Early window of diabetes deter ...... ntified by noninvasive imaging
@ast
Early window of diabetes deter ...... ntified by noninvasive imaging
@en
P2093
P2860
P356
P1433
P1476
Early window of diabetes deter ...... ntified by noninvasive imaging
@en
P2093
Christophe Benoist
Diane Mathis
Wenxian Fu
P2860
P304
P356
10.1038/NI.2233
P407
P577
2012-02-26T00:00:00Z