The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.
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A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivationTowards an understanding of the herpes simplex virus type 1 latency-reactivation cycleThe locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice.The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivationReplication of herpes simplex virus type 1 within trigeminal ganglia is required for high frequency but not high viral genome copy number latency.Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue cultureIdentification of a novel herpes simplex virus type 1 transcript and protein (AL3) expressed during latency.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis.The herpes simplex virus type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c miceA mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.Infection of cattle with a bovine herpesvirus 1 strain that contains a mutation in the latency-related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency.Herpes simplex virus type 1 and bovine herpesvirus 1 latency.The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanismA herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation.Experimental investigation of herpes simplex virus latencyThe spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript.A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1High-dose ocular infection with a herpes simplex virus type 1 ICP34.5 deletion mutant produces no corneal disease or neurovirulence yet results in wild-type levels of spontaneous reactivation.A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies.Increased neurovirulence and reactivation of the herpes simplex virus type 1 latency-associated transcript (LAT)-negative mutant dLAT2903 with a disrupted LAT miR-H2The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic RabbitsHerpes simplex virus type 1 serum neutralizing antibody titers increase during latency in rabbits latently infected with latency-associated transcript (LAT)-positive but not LAT-negative viruses.Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival.
P2860
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P2860
The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The region of the herpes simpl ...... d in spontaneous reactivation.
@ast
The region of the herpes simpl ...... d in spontaneous reactivation.
@en
type
label
The region of the herpes simpl ...... d in spontaneous reactivation.
@ast
The region of the herpes simpl ...... d in spontaneous reactivation.
@en
prefLabel
The region of the herpes simpl ...... d in spontaneous reactivation.
@ast
The region of the herpes simpl ...... d in spontaneous reactivation.
@en
P2093
P2860
P1433
P1476
The region of the herpes simpl ...... ed in spontaneous reactivation
@en
P2093
A B Nesburn
K Chokephaibulkit
N M Sawtell
R L Thompson
S L Wechsler
S M Slanina
P2860
P304
P407
P577
1996-01-01T00:00:00Z