Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate.
about
Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsRAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytesT cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3GTyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillinAssociation of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytesLigation of the T-cell Antigen Receptor (TCR) Induces Association of hSos1, ZAP-70, Phospolipase C- 1, and Other Phosphoproteins with Grb2 and the -Chain of the TCRRequirements for localization of p130cas to focal adhesions.ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domainsT cell receptor- and beta 1 integrin-mediated signals synergize to induce tyrosine phosphorylation of focal adhesion kinase (pp125FAK) in human T cellsInterleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB).Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor functionAdhesion to fibronectin promotes the activation of the p125(FAK)/Zap-70complex in human T cells.T-lymphocyte interactions with endothelium and extracellular matrix.Reconstitution of high affinity IgE receptor-mediated secretion by transfecting protein tyrosine kinase pp125FAK.The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins.The activation state of the integrin alpha IIb beta 3 affects outside-in signals leading to cell spreading and focal adhesion kinase phosphorylation.RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells.T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70.Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling.Nocodazole inhibits signal transduction by the T cell antigen receptor.Induction of PYK-2 phosphorylation during LFA-1/ICAM-1-dependent homotypic adhesion of fresh human B-cells.
P2860
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P2860
Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@ast
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@en
type
label
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@ast
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@en
prefLabel
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@ast
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@en
P2093
P2860
P356
P1476
Lymphocyte antigen receptor ac ...... ted tyrosine kinase substrate.
@en
P2093
P2860
P304
10484-10487
P356
10.1073/PNAS.91.22.10484
P407
P577
1994-10-01T00:00:00Z