Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells
about
ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinityMechanism of activation for Zap-70 catalytic activityAnalysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonanceThe kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localizationRegulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin ADual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptorGRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulationTyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cellsBinding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsAssociation of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transductionSyk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complexA Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motifSignaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphataseCloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinaseAssociation of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytesInteraction of p72syk with the gamma and beta subunits of the high-affinity receptor for immunoglobulin E, Fc epsilon RISequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling.Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell lineGenetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line.S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes.Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes.Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.Kinetic proofreading in T-cell receptor signal transduction.A discrete affinity-driven elevation of ZAP-70 kinase activity initiates negative selection.p56lck-independent activation and tyrosine phosphorylation of p72syk by T-cell antigen receptor/CD3 stimulation.Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains.Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex.Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate.Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain.ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domainsZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulationp56lck interacts via its src homology 2 domain with the ZAP-70 kinase.Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation.Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell developmentPartially phosphorylated T cell receptor zeta molecules can inhibit T cell activation.Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice.Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.Copresentation of natural HIV-1 agonist and antagonist ligands fails to induce the T cell receptor signaling cascade.
P2860
Q24306545-381797E3-290E-4B3A-B2E8-75C35FD3F951Q24318354-3E42FCE4-834F-4ECF-A9AF-C6DE281123D9Q24319958-E3B9F3E9-6C19-4341-8E79-23239D4628E8Q24324202-3DF9974F-7846-4160-B391-CD617F9AFA86Q24534698-6CAF42A1-229D-4145-9850-F25D07B74651Q24597028-3F005013-778D-40CF-ABBC-73C9015A3B0FQ24611910-4807BAB6-01C8-444D-B556-5FF3F7C99CE5Q24649084-A45C1A0F-3D32-4C80-BADB-21F12F560DF0Q24652248-43C7A327-86D5-48FA-8B8A-96E05DB55F03Q24671794-8459E9BA-F561-4C2F-AAE0-975D3BB0D28CQ24678927-CAE60D88-BC37-497D-94E2-7C5E21B1F8A4Q27664925-1E7C9B5B-5E74-4759-822C-63A7069A2894Q28507195-826FE43C-C49B-42A5-9FBB-64EA13C2BFC3Q28507508-EC397BFF-A5B6-4D31-ABBF-3E49C66EFA63Q28576785-B340D68F-64A7-438A-B2C8-89577F793BFAQ28585310-991F965B-8476-4B2A-BBB7-E12906745B59Q28611006-FE1B4E22-FEB5-4C24-A0CB-F93CB2B1C494Q30175249-8D5A4D2A-8110-40B8-B783-F76B54A6A314Q33606123-56855E15-C75C-4D4A-8401-EDF8B9BEAD1AQ33772316-858B573B-DD86-4FE7-B87C-D3FFF879A1D1Q33887288-8C6C0B8C-BC33-4FCD-87E1-ED96ECDEF74AQ33957330-A560F6F2-60E8-428D-99E1-7F5A94591572Q34048875-55A61FF6-4AF5-4440-A496-FD450D573861Q34285825-871ED830-0AB2-4177-BFB0-543FEF28D340Q34666349-C8C0CA03-E441-4880-965F-7FC73F88D267Q35430424-F4D42AE5-44C8-421A-930C-71BF3AA19F3AQ35591730-49FF8F71-10DD-4231-BF69-E70BF028D8E0Q35800446-E5D05A6A-DC10-4D8C-9DEC-2014918D455EQ35857735-9B140C7F-44E4-414F-B9EE-6649D68C3C2BQ35886042-E6B04D44-5EAC-474F-B831-0B440055A56CQ36266883-E2CF46A4-5A36-40E3-90C9-8D52630F4669Q36288209-3FEFB93C-31DE-4328-9AFC-AB6E9DD360D3Q36362929-65C29718-2C47-4234-8FDE-7386DE6EC905Q36365800-C88020C7-4EED-489A-99D5-ECD15608C2BCQ36367209-58FD3E3B-43A6-4C1A-9BAC-E743A70B384FQ36369507-88E1B98E-1AFD-4CD4-9C63-BA6A2A027E59Q36375671-48698C7B-04CF-41D7-A70A-385452862B7AQ36380617-0413FDED-97CB-494F-9DDD-11151EFC6F33Q36380874-C2E44338-A2FE-4224-8993-0C27C01E22F1Q36475932-8CA30F73-A399-47B4-B7BE-36E6EDECACC8
P2860
Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells
description
1993 nî lūn-bûn
@nan
1993 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@ast
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@en
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@nl
type
label
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@ast
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@en
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@nl
prefLabel
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@ast
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@en
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@nl
P2093
P3181
P1476
Tandem SH2 domains of ZAP-70 b ...... from activated Jurkat T cells
@en
P2093
L E Samelson
S Desiderio
P304
P3181
P407
P577
1993-09-15T00:00:00Z