The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
about
A Comparative Analysis of Genetic and Epigenetic Events of Breast and Ovarian Cancer Related to TumorigenesisThe T-box gene family: emerging roles in development, stem cells and cancerThe Caenorhabditis elegans T-box factor MLS-1 requires Groucho co-repressor interaction for uterine muscle specificationThe role of T‑box genes in the tumorigenesis and progression of cancer (Review)T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesisSignalling pathways implicated in early mammary gland morphogenesis and breast cancer.Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance.TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model.Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.Human breast progenitor cell numbers are regulated by WNT and TBX3.Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma.The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.The Highly Homologous T-Box Transcription Factors, TBX2 and TBX3, Have Distinct Roles in the Oncogenic ProcessTbx2a is required for specification of endodermal pouches during development of the pharyngeal archesGli activity is critical at multiple stages of embryonic mammary and nipple development.The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinasesA novel role for the T-box transcription factor Tbx1 as a negative regulator of tumor cell growth in mice.A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.T-box 2 expression predicts poor prognosis in gastric cancer.The ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb developmentThe transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancerTBX3 promotes human embryonic stem cell proliferation and neuroepithelial differentiation in a differentiation stage-dependent mannerT-box factors determine cardiac design.Genome-wide association analysis identifies three new breast cancer susceptibility loci.TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle.Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion.Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinomaThe oncogenic TBX3 is a downstream target and mediator of the TGF-β1 signaling pathwayThe T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypesEffect of silencing the T‑Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells.Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion.PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration.The transcription factors TBX2 and TBX3 interact with human papillomavirus 16 (HPV16) L2 and repress the long control region of HPVsPutative Breast Cancer Driver Mutations in TBX3 Cause Impaired Transcriptional Repression.Diverse functional networks of Tbx3 in development and diseaseTBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.Prognostic significance of expression of epithelial-mesenchymal transition driver brachyury in breast cancer and its association with subtype and characteristics.TBX2 expression is associated with platinum-sensitivity of ovarian serous carcinoma.Expression of epithelial-mesenchymal transition driver brachyury and status of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in predicting treatment responses to neoadjuvant chemotherapy of breast cancer.
P2860
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P2860
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@ast
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@en
type
label
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@ast
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@en
prefLabel
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@ast
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@en
P1476
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
@en
P2093
Erin Grothey
Matthew Rowley
P304
P356
10.1023/B:JOMG.0000037156.64331.3F
P577
2004-04-01T00:00:00Z
P6179
1035935489