The virion host shutoff protein of herpes simplex virus type 1: messenger ribonucleolytic activity in vitro
about
mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F.Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4HThe virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase AHSV-1 tegument protein and the development of its genome editing technologyAlphaherpesvirus Subversion of Stress-Induced Translational ArrestA ribonucleoprotein complex protects the interleukin-6 mRNA from degradation by distinct herpesviral endonucleasesCrystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoffPlus- and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structuresThe herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extractsHerpes simplex virus infection stabilizes cellular IEX-1 mRNA.The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice.Evidence that herpes simplex virus VP16 is required for viral egress downstream of the initial envelopment event.Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein.Disruption of virion host shutoff activity improves the immunogenicity and protective capacity of a replication-incompetent herpes simplex virus type 1 vaccine strain.Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity.mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor.Translational control of viral gene expression in eukaryotesThe virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.Coordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1.Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNaseVaricella-zoster virus (VZV) ORF17 protein induces RNA cleavage and is critical for replication of VZV at 37 degrees C but not 33 degrees C.The 2-kilobase intron of the herpes simplex virus type 1 latency-associated transcript has a half-life of approximately 24 hours in SY5Y and COS-1 cells.mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteinsOncolytic herpes simplex virus 1 encoding 15-prostaglandin dehydrogenase mitigates immune suppression and reduces ectopic primary and metastatic breast cancer in mice.Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 geneHerpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virionsHerpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo.Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesisExpression and function of the equine herpesvirus 1 virion-associated host shutoff homolog.Inhibition of human immunodeficiency virus replication by the herpes simplex virus virion host shutoff protein.Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimerasInteraction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNAThe "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection.Deletion of the herpes simplex virus 1 UL49 gene results in mRNA and protein translation defects that are complemented by secondary mutations in UL41.Roles of nucleic acid substrates and cofactors in the vhs protein activity of pseudorabies virus.
P2860
Q24532995-0078B21F-53CD-4AA7-B162-43D0E2C63696Q24533337-064F6F62-926F-4A19-9217-CF44CA899EABQ24623749-229781D6-C6A1-44CF-85C8-F7415EECAFF7Q24673746-C31A50F2-B2AC-4623-9045-4231BC9C3758Q26747146-8EEB26EF-2D23-4FD7-A939-5F2B844D051CQ26753006-4BEBCB0B-8963-4A3E-BB9F-13EA1CEF3018Q27319922-5177AFB0-2E22-4DDD-A894-70EF72802562Q27667301-8B83DF17-53D4-4DBC-839F-B239BCE6CC53Q33632158-6B07D4EE-2A3E-4E3A-A237-A9D5882012EEQ33648831-C07DB7F0-61A8-41E5-BF3D-DD39C8C9F6EAQ33707517-F4068593-52EE-429D-9A7E-78AE3FC11711Q33785225-C4577E12-E288-4CF2-8E00-78B844483E4FQ33802243-79C6A1B1-5EF8-4726-B001-6181E64A1B54Q33807388-273543A4-138F-4A3B-A7D0-CDB3B947AF28Q33822743-24885ED0-F1C8-419F-BFAF-322FB459D76CQ33822939-B91C895D-52C5-49C4-8BCD-366BA2EFB99BQ33826884-D050A387-1F86-4B0F-896D-D37E78610E61Q33836046-1CAB6E88-3165-48CA-8CC4-96A7D7145032Q33847834-EA1BA8D9-E8A6-4EE1-9D59-1CF18EB53F16Q33935121-AE97AEA0-9531-49C3-BC62-B33C1C12E915Q33990628-29E19BE7-A9AA-4E01-B005-8D4022599A32Q34064226-6C26D91F-A525-49E6-AB12-49C758611F59Q34120868-B32F46C9-5920-43D7-9408-EC7496CE8112Q34349183-68F985FA-6861-4458-A39F-3DF25F9FA022Q34357809-41BF4165-BFE1-4044-8A3F-858ADA0B2BB0Q34362360-ECBADA21-B8FB-4BE7-8061-EF0518A7A8C2Q34479586-E921945E-10E4-4B9E-8E1C-F70CA6907C6FQ35077655-10508566-5743-4B87-B3AD-32B292907235Q35101393-55F9A803-C642-4482-8A26-F96E42F13561Q35543196-219CD31E-D9CB-4FAC-BDEE-C98BF01D5CEFQ35635097-1DC59CC7-CE9B-4AF8-AAF6-568952119EE9Q35803282-A2ED0925-1663-4FC2-BC2A-5900424E341DQ35866710-9D4B9AEC-606B-45A3-A35E-84215D91F98FQ35873762-851FAADB-3AAB-4EE7-8FF5-C19A817F5507Q35888626-632640FC-61F9-4CE4-88E6-E0B9CA60EDC7Q35894630-0BBB3597-655C-4C00-BE5D-0E0DB48878E8Q35901199-9B2FB1E8-D88C-49DE-A50D-FD4E0FF8DB57Q36154936-6EF469F6-8B06-49FB-8C67-D75F2F60F574Q36363780-F5B2953D-677D-47BC-80C8-3548329BDEA8Q36424836-83A03B17-0472-4969-AE26-508980CFF2C6
P2860
The virion host shutoff protein of herpes simplex virus type 1: messenger ribonucleolytic activity in vitro
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The virion host shutoff protei ...... onucleolytic activity in vitro
@ast
The virion host shutoff protei ...... onucleolytic activity in vitro
@en
type
label
The virion host shutoff protei ...... onucleolytic activity in vitro
@ast
The virion host shutoff protei ...... onucleolytic activity in vitro
@en
prefLabel
The virion host shutoff protei ...... onucleolytic activity in vitro
@ast
The virion host shutoff protei ...... onucleolytic activity in vitro
@en
P2093
P2860
P1433
P1476
The virion host shutoff protei ...... onucleolytic activity in vitro
@en
P2093
P2860
P304
P407
P577
1996-04-01T00:00:00Z