Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16.
about
Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways.Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets familyHuman scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligaseHuman papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityHuman Papillomavirus: Current and Future RNAi Therapeutic Strategies for Cervical CancerStudy designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cellsFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesPapillomavirus E6 oncoproteins.Gene expression profile of cervical and skin tissues from human papillomavirus type 16 E6 transgenic mice.Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligaseThe human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals.Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation.Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle.Cutaneous HPV23 E6 prevents p53 phosphorylation through interaction with HIPK2.Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis.Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cellsPrimary human cervical carcinoma cells require human papillomavirus E6 and E7 expression for ongoing proliferation.Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity.Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein.Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytesDown-regulation of transforming growth factor-beta type II receptor (TGF-betaRII) protein and mRNA expression in cervical cancer.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesLarge-scale analysis of protein expression changes in human keratinocytes immortalized by human papilloma virus type 16 E6 and E7 oncogenes.Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function.Low risk HPV-E6 traps p53 in the cytoplasm and induces p53-dependent apoptosis.Stem Cell Properties of Normal Human Keratinocytes Determine Transformation Responses to Human Papillomavirus 16 DNA.
P2860
Q24293315-A9AA122C-12BB-434A-867D-E4C194C72B69Q24319000-7C7BACBD-E12C-4A17-8D3B-9841832881D1Q24551145-F6CEFE0E-C2F6-4306-B1E3-D9CB6DF25515Q24599944-A3429A65-99FC-4130-80C8-DD905CE90EE7Q26799484-0E03677A-2B69-466F-AFB9-BA0DD13C686FQ26852739-4D1265AC-3874-4758-A708-B432C423923AQ28078631-2372B8F0-DFEB-4159-B5AD-A05B09FEA717Q30410553-3EA273E1-FF25-49D9-A195-195C740460F1Q33387408-9575EA20-57D8-4F09-8CC7-0893F7729E6FQ33807681-37474EC9-A40D-4E55-A7A2-8E62CA16B179Q33815722-5B190ACF-C715-4CE5-ADE9-07FD783DE20BQ33859710-65A38C05-4C14-49B5-BDB0-2F17D288968CQ34045582-C7F52C9D-0712-40B9-A2B5-7BA5B875FFC5Q34081681-B48B4B2B-D2C6-4F06-A23D-E58D08DB6A4CQ34153391-23E3468B-F9D2-44F6-9137-6D55AFF4CAF8Q34226397-718DD21C-4C47-4416-94FE-53309CE4BC7BQ35589596-55CB5DE3-FAE7-4551-A475-938EE60F7790Q35789014-3FF4CA40-1181-4914-9B46-554C4B45BFB1Q35797390-86EA4F95-8F20-466C-A299-5BAAA8B96068Q35812040-A3FE958F-5F20-4597-84F3-6D854D5CC888Q36470168-13CEC966-173C-44BC-91E0-84405AB0CC1CQ36989890-7E1CD687-1373-4A67-9460-E4BB8B19F10FQ37348474-3F8D6B7A-057A-42F0-929B-C006CB905C74Q39457857-61953C74-FC49-4089-8E21-CDBF130F02BEQ39998431-379253C9-1945-4C39-81C2-ED3CDD8EAA1CQ41810748-70B2046B-769C-4C12-AD46-47EA8D1A15B6Q54246626-AC89190F-429E-475D-A263-38505B8A352A
P2860
Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@ast
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@en
type
label
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@ast
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@en
prefLabel
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@ast
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@en
P2860
P1433
P1476
Serum- and calcium-induced dif ...... human papillomavirus type 16.
@en
P2093
P2860
P304
P407
P577
1996-05-01T00:00:00Z