Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
about
Isoprenylcysteine carboxyl methyltransferase deficiency in micePrenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cellsRab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5AGuanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases.Overexpression of a mutant form of EhRabA, a unique Rab GTPase of Entamoeba histolytica, alters endoplasmic reticulum morphology and localization of the Gal/GalNAc adherence lectinPrelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.Membrane targeting of Rab GTPases is influenced by the prenylation motifProtein prenyltransferases: anchor size, pseudogenes and parasites.Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.Single prenyl-binding site on protein prenyl transferases.Fungal lipopeptide mating pheromones: a model system for the study of protein prenylationThe role of the hypervariable C-terminal domain in Rab GTPases membrane targeting.Simvastatin inhibits protein isoprenylation in the brain.Molecular control of Rab activity by GEFs, GAPs and GDI.Identification and validation of eukaryotic aspartate and glutamate methylation in proteins.Characterization of prenylcysteine methyltransferase in insulin-secreting cellsTopology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe.Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma).Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasisMechanism of digeranylgeranylation of Rab proteins. Formation of a complex between monogeranylgeranyl-Rab and Rab escort protein.Rab1a and multiple other Rab proteins are associated with the transcytotic pathway in rat liver.Neuropeptide Y expression, localization and cellular transducing effects in HUVEC.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT.Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation.
P2860
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P2860
Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@ast
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@en
type
label
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@ast
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@en
prefLabel
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@ast
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@en
P2093
P2860
P356
P1476
Geranylgeranylated Rab protein ...... vine brain membranes in vitro.
@en
P2093
J L Goldstein
M C Seabra
T E Smeland
P2860
P304
10712-10716
P356
10.1073/PNAS.91.22.10712
P407
P577
1994-10-01T00:00:00Z