Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A - Wikidata - wikimedia - TriplyDB

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

http://www.wikidata.org/entity/Q24564547

about

A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases Structure of mammalian protein geranylgeranyltransferase type-I The putative "switch 2" domain of the Ras-related GTPase, Rab1B, plays an essential role in the interaction with Rab escort protein Intracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins.Reaction path of protein farnesyltransferase at atomic resolution Equine herpesvirus protein E10 induces membrane recruitment and phosphorylation of its cellular homologue, bcl-10 Chlamydia pneumoniae inclusion membrane protein Cpn0585 interacts with multiple Rab GTPases Protein prenyltransferases Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy Rab27a regulates the peripheral distribution of melanosomes in melanocytes Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity Therapeutic intervention based on protein prenylation and associated modifications Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma.The GTPase Rap1 regulates phorbol 12-myristate 13-acetate-stimulated but not ligand-induced beta 1 integrin-dependent leukocyte adhesion.Structure, mechanism and function of prenyltransferases.Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues.Multiple factors contribute to inefficient prenylation of Rab27a in Rab prenylation diseases.Prenylation of Rab GTPases: molecular mechanisms and involvement in genetic disease.Deficient geranylgeranylation of Ram/Rab27 in choroideremia.Blocking oncogenic Ras signaling for cancer therapy.The GTPase Rab4 interacts with Chlamydia trachomatis inclusion membrane protein CT229.Membrane targeting of Rab GTPases is influenced by the prenylation motif COPI recruitment is modulated by a Rab1b-dependent mechanism Therapeutic efficacy of prenylation inhibitors in the treatment of myeloid leukemia.MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.Small GTPases Rab8a and Rab11a Are Dispensable for Rhodopsin Transport in Mouse Photoreceptors Lipid-modified proteins as biomarkers for cardiovascular disease: a review.Single prenyl-binding site on protein prenyl transferases.Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells.Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.Rab proteins and the secretory pathway: the case of rab18 in neuroendocrine cells.GDP dissociation inhibitor serves as a cytosolic acceptor for newly synthesized and prenylated Rab5.KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma.Regulation of β2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor Geranylgeranyltransferase I of Candida albicans: null mutants or enzyme inhibitors produce unexpected phenotypes.Alkynyl-farnesol reporters for detection of protein S-prenylation in cells.SopE acts as an Rab5-specific nucleotide exchange factor and recruits non-prenylated Rab5 on Salmonella-containing phagosomes to promote fusion with early endosomes.Rab24 is an atypical member of the Rab GTPase family. Deficient GTPase activity, GDP dissociation inhibitor interaction, and prenylation of Rab24 expressed in cultured cells.

P2860

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P2860

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

http://www.wikidata.org/entity/Q24564547

description

1994 nî lūn-bûn

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1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1994年の論文

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1994年学术文章

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1994年学术文章

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1994年学术文章

@zh-hans

1994年学术文章

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1994年学术文章

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1994年學術文章

@yue

name

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@ast

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

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Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

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type

label

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@ast

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@en

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@nl

prefLabel

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@ast

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@en

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

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PNAS.91.25.11963

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Rab geranylgeranyl transferase ...... TPases Rab1A, Rab3A, and Rab5A

@en

P2093

C C Farnsworth

http://www.w3.org/2001/XMLSchema#string

J A Glomset

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L H Ericsson

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M H Gelb

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P2860

The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion

Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Isoprenoid modification of rab proteins terminating in CC or CXC motifs

Dependence of Ypt1 and Sec4 membrane attachment on Bet2.

Cloning of a gene that is rearranged in patients with choroideraemia

REP-2, a Rab escort protein encoded by the choroideremia-like gene

All ras proteins are polyisoprenylated but only some are palmitoylated

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys

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11963-11967

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scholarly article

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4067548

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10.1073/PNAS.91.25.11963

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P433

25

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91

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P50

Miguel C. Seabra

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1994-12-01T00:00:00Z

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15206807

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7991565

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45356

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