Mutant protein A30P α-synuclein adopts wild-type fibril structure, despite slower fibrillation kinetics
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Site-specific perturbations of alpha-synuclein fibril structure by the Parkinson's disease associated mutations A53T and E46KMutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregationPhysical and structural basis for polymorphism in amyloid fibrilsAmyloid polymorphism: structural basis and neurobiological relevance.Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutationHigh resolution structural characterization of Aβ42 amyloid fibrils by magic angle spinning NMR.Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutantsComparison of strategies for non-perturbing labeling of α-synuclein to study amyloidogenesis.Efficient resonance assignment of proteins in MAS NMR by simultaneous intra- and inter-residue 3D correlation spectroscopy.α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.ɑ-Synuclein strains and the variable pathologies of synucleinopathies.Investigational α-synuclein aggregation inhibitors: hope for Parkinson's disease.Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence.Looking at the recent advances in understanding α-synuclein and its aggregation through the proteoform prism.In vitro aggregation assays for the characterization of α-synuclein prion-like properties.A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein FibrilsWhat Does Solid-State NMR Tell Us about Amyloid Structures?
P2860
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P2860
Mutant protein A30P α-synuclein adopts wild-type fibril structure, despite slower fibrillation kinetics
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@ast
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@en
type
label
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@ast
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@en
prefLabel
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@ast
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@en
P2093
P2860
P356
P1476
Mutant protein A30P α-synuclei ...... e slower fibrillation kinetics
@en
P2093
Chad M Rienstra
Gemma Comellas
Kathryn D Kloepper
Luisel R Lemkau
Wendy S Woods
P2860
P304
11526-11532
P356
10.1074/JBC.M111.306902
P407
P50
P577
2012-02-09T00:00:00Z