Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
about
Differential roles for snapin and synaptotagmin in the synaptic vesicle cycleDirect interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha1A subunit of the P/Q-type calcium channelFunctional and biochemical analysis of the C2 domains of synaptotagmin IVSynaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cellsCalcium control of neurotransmitter releaseComplexin clamps asynchronous release by blocking a secondary Ca(2+) sensor via its accessory α helixActivity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous releaseDrosophila tools and assays for the study of human diseasesComplexins: small but capableAP180 maintains the distribution of synaptic and vesicle proteins in the nerve terminal and indirectly regulates the efficacy of Ca2+-triggered exocytosisComplexin controls spontaneous and evoked neurotransmitter release by regulating the timing and properties of synaptotagmin activityIdentification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cellsDelineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagminRat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusionThe AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosisSynaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses.Ring-like oligomers of Synaptotagmins and related C2 domain proteinsAxonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screenAutapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I.100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the futureProteins involved in synaptic vesicle trafficking.Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster.Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis.Synaptotagmin I is a molecular target for lead.Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction.Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1.Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathyCa2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivoFunctional and physical coupling of voltage-sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism.Calcium sensitive ring-like oligomers formed by synaptotagminCa2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1Depolarization-induced Ca2+ entry preferentially evokes release of large quanta in the developing Xenopus neuromuscular junction.Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I.Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter releaseRole of synaptotagmin in Ca2+-triggered exocytosis.Visualization of synaptotagmin I oligomers assembled onto lipid monolayers.Modulation of synaptic plasticity by stress and antidepressants.Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo.
P2860
Q21133645-CC69EC7F-F371-4B2D-AE2F-4BFCF747D540Q24532479-08C4AC72-2A5A-428D-971B-66A499A8AD29Q24647716-4D0E003F-CA88-4F00-9F4E-D1083743875CQ24674990-C8F74475-43FF-4C19-8BAF-DBF3AECB80D6Q26269884-DA0EB532-574B-4B25-9032-21BC62737322Q26269900-B0834F63-DBE0-4187-A2EE-45981A017269Q26269914-172E8811-69D9-4501-99B8-F94B1373F5DCQ26269916-E5E6E37F-0364-4866-B57D-C23EE28927DCQ26765022-51B9C77C-E32B-4B5A-996A-63C15AE83B60Q26798363-9E185930-C395-4CB9-B6E8-B42506ED1C90Q28250132-E9DC2C73-A63C-4D60-B808-F0D741550444Q28281363-ADAC8732-EC5D-4548-9779-9874FB553094Q28565771-90101F5D-CE44-4D09-84BD-A61ABD783ECAQ28577061-A9F4098A-9A14-48AE-9A68-96286C52077BQ28580444-E8CD0A5C-54DD-42F1-BB66-5B23768DDBEBQ28582288-84194C47-9A24-4424-BFD4-C656C19BD8BFQ28586487-0837C8E8-3AE6-41E5-9755-889E77A3C7FBQ28831105-A74E9193-5AA5-4BD5-9A22-AA7A03A876EDQ30513861-6AA360E3-03B6-4B5F-A648-06EB2B40AA33Q33465411-163CB0BA-C9CE-46E3-8FBC-87B2C636A5C5Q33615730-CBB08B0F-2989-4E62-BA66-666F1CD45FFEQ33750208-78EF9DB7-1AA6-44FA-B06F-CA745E0288FBQ33771757-D0A524D0-9499-41CD-8E66-0A764153CEDBQ33936001-8DE661D5-519A-4659-9E61-88EB69BAA73CQ33939019-0E2A9C74-28BD-4E75-954D-0903AC7CD635Q34068556-953849A0-D891-4006-A6F6-603FCF4F3D52Q34093007-9627E272-B836-4C9A-AD30-00C4765173BFQ34146828-14BFC992-B07A-463D-B631-502079AEF5F1Q34171564-C94A4052-40C2-4372-8EBA-B1259B1DF1B1Q34255538-9A2C819D-A37C-4C05-BE8F-0B91E43C87B3Q34281080-C0E942BA-FF3E-4E6A-B138-B1DB1FEEC723Q34305768-296820F3-0A6C-4983-AE72-EB982E93B04CQ34379680-CF8077DE-D9B9-4018-B226-851F82E4CF98Q34447415-D2E00859-4510-488F-ABD3-9650BFBA7027Q34572301-D2BC86D4-4C46-4F0D-BF5A-DB51713AAE73Q34605918-E67BFA5D-12A4-4806-9C08-2072D0ADA4A9Q34669186-7B73323C-A423-4463-9E03-7ADD2974E104Q34763458-8BCB7B0E-D323-4457-A12B-AEFB9E0691B8Q34785753-91CA8A42-560D-4CBC-96DA-1506B39B1C10Q34974283-4339FDF3-30CF-4ECD-8722-E8C086DA1ADA
P2860
Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@ast
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@en
type
label
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@ast
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@en
prefLabel
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@ast
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@en
P2860
P356
P1476
Calcium dependence of neurotra ...... osophila synaptotagmin mutants
@en
P2860
P304
10888-10892
P356
10.1073/PNAS.91.23.10888
P407
P577
1994-11-01T00:00:00Z