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Design, Synthesis, Calorimetry, and Crystallographic Analysis of 2-Alkylaminoethyl-1,1-bisphosphonates as Inhibitors of Trypanosoma cruzi Farnesyl Diphosphate SynthaseAortic stenosis: insights on pathogenesis and clinical implications.Persistence of 1,25D-induced hypercalciuria in alendronate-treated genetic hypercalciuric stone-forming rats fed a low-calcium dietInositol hexakisphosphate inhibits osteoclastogenesis on RAW 264.7 cells and human primary osteoclasts.Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.Bisphosphonates induce senescence in normal human oral keratinocytes.Changes in bone remodelling and antifracture efficacy of intermittent bisphosphonate therapy: implications from clinical studies with ibandronate.2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase.1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthaseOsteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Gα(12) or constitutively active RhoASynthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthaseDesign, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents.Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosisVariations in nanomechanical properties and tissue composition within trabeculae from an ovine model of osteoporosis and treatment.Inhibition of Osteoclast Differentiation and Bone Resorption by Bisphosphonate-conjugated Gold Nanoparticles.The differential effects of bisphosphonates, SERMS (selective estrogen receptor modulators), and parathyroid hormone on bone remodeling in osteoporosis.Comparative effects of antiresorptive agents on bone mineral density and bone turnover in postmenopausal womenHow to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.Biphosphonates-related osteonecrosis of the jaw: Clinical and physiopathological considerations.Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of Pathology Linked to G6PD Deficiency and Sulfomucins.Alendronate preserves femoral head shape and height/length ratios in an experimental rat model: A computer-assisted analysis.New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase.The effect of alendronate on proteome of hepatocellular carcinoma cell lines.Bisphosphonates and atypical subtrochanteric fractures of the femur.Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.Impact of Bisphosphonate on Orthodontic tooth movement and osteoclastic count: An Animal Study.Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes.Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Nitrogen-containing bisphosphonate mechanism of action.
@ast
Nitrogen-containing bisphosphonate mechanism of action.
@en
type
label
Nitrogen-containing bisphosphonate mechanism of action.
@ast
Nitrogen-containing bisphosphonate mechanism of action.
@en
prefLabel
Nitrogen-containing bisphosphonate mechanism of action.
@ast
Nitrogen-containing bisphosphonate mechanism of action.
@en
P1476
Nitrogen-containing bisphosphonate mechanism of action
@en
P2093
Alfred A Reszka
Gideon A Rodan
P304
P577
2004-09-01T00:00:00Z