1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase

1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase

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http://www.wikidata.org/entity/Q36280536
Studies of the Effectiveness of Bisphosphonate and Vanadium-Bisphosphonate Compounds In Vitro against Axenic Leishmania tarentolae.2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase.The N-terminus and the chain-length determination domain play a role in the length of the isoprenoid product of the bifunctional Toxoplasma gondii farnesyl diphosphate synthase.Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents.New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase.New antibacterials for the treatment of toxoplasmosis; a patent review.Screening for small molecule inhibitors of Toxoplasma gondii.Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase.Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015).Antiparasitic Activity of Sulfur- and Fluorine-Containing Bisphosphonates against Trypanosomatids and Apicomplexan Parasites.Presence of a plant-like proton-translocating pyrophosphatase in a scuticociliate parasite and its role as a possible drug target.α-Methylation enhances the potency of isoprenoid triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.
P2860

1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase

Item
http://www.wikidata.org/entity/Q36280536
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@ast
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@en
type
label
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@ast
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@en
prefLabel
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@ast
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
1-(Fluoroalkylidene)-1,1-bisph ...... arnesyl pyrophosphate synthase
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932