Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
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CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemiaEGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradationA missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemiaTreatment dilemmas of cetuximab combined with chemotherapy for metastatic colorectal cancerThe renal channelopathiesEpidermal growth factor, from gene organization to bedsideInduction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulinEpidermal growth factor: a new therapeutic target in glomerular disease.The roles of post-translational modifications in the context of protein interaction networksFamilial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC): compound heterozygous mutation in the claudin 16 (CLDN16) gene.Understanding, recognizing, and managing toxicities of targeted anticancer therapies.Genetic causes of hypomagnesemia, a clinical overviewRenal magnification by EGFHypomagnesemia: a clinical perspective.Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular SystemFrom wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment.Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.The TRPM6/EGF pathway is downregulated in a rat model of cisplatin nephrotoxicity.Distal convoluted tubuleHNF1B mutations associate with hypomagnesemia and renal magnesium wasting.Cellular magnesium homeostasis.Risk/benefit profile of panitumumab-based therapy in patients with metastatic colorectal cancer: evidence from five randomized controlled trials.Physiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations.Nephrotoxicity of recent anti-cancer agents.Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity.Electrolyte disorders assessment in solid tumor patients treated with anti-EGFR monoclonal antibodies: a pooled analysis of 25 randomized clinical trials.Regulation of magnesium balance: lessons learned from human genetic diseaseSex differences in proximal and distal nephron function contribute to the mechanism of idiopathic hypercalcuria in calcium stone formers.When EGF is offside, magnesium is wasted.Epidermal growth factor cytoplasmic domain affects ErbB protein degradation by the lysosomal and ubiquitin-proteasome pathway in human cancer cells.Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: A comparative studyAssessment of frequency and severity of hypomagnesemia in patients with metastatic colorectal cancer treated with cetuximab, with a review of the literature.TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions.Transformation of polarized epithelial cells by apical mistrafficking of epiregulinDeficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.Incidence and risk of hypomagnesemia in advanced cancer patients treated with cetuximab: A meta-analysis.Calciotropic and magnesiotropic TRP channels.Molecular determinants of magnesium homeostasis: insights from human diseaseThe role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology
P2860
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P2860
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@ast
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@en
type
label
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@ast
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@en
prefLabel
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@ast
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@en
P2093
P2860
P356
P1476
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
@en
P2093
Dennis van den Berg
Eric van Cutsem
Jenny van der Wijst
Joost G Hoenderop
Lambertus P van den Heuvel
Nine V Knoers
René J Bindels
Rob Janssen
Stéphanie Thébault
Wouter M Tiel Groenestege
P2860
P304
P356
10.1172/JCI31680
P407
P577
2007-08-01T00:00:00Z