Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
about
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme targetSynthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.Protein trafficking through the endosomal system prepares intracellular parasites for a home invasionMolecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infectionsSalicylanilide inhibitors of Toxoplasma gondiiModification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.Drugs in development for toxoplasmosis: advances, challenges, and current status.Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivoScreening for small molecule inhibitors of Toxoplasma gondii.Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.In vitro activity of the interaction between taxifolin (dihydroquercetin) and pyrimethamine against Toxoplasma gondii.Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles.In vitro antagonistic and indifferent activity of combination of 3-deoxyanthocyanidins against Toxoplasma gondii.Phylogeny and Evolution
P2860
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P2860
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@ast
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en-gb
type
label
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@ast
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en-gb
prefLabel
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@ast
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en-gb
P2093
P2860
P50
P356
P1476
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
@en
P2093
Alan P Kozikowski
Alina Fomovska
Caroline Sommerville
David W Rice
Ernest J Mui
Gustavo A Afanador
Jennifer M Auschwitz
Jozef Stec
Kamal El Bissati
Mark R Hickman
P2860
P304
P356
10.1128/AAC.06450-11
P407
P577
2012-02-21T00:00:00Z