The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration.
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Retinol Dehydrogenases Regulate Vitamin A Metabolism for Visual FunctionAlpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activityMetabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retinaPBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced DamageIsolation and characterization of a spontaneously immortalized bovine retinal pigmented epithelial cell line.Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair.Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice.Pharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment.An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brainKey enzymes of the retinoid (visual) cycle in vertebrate retinaRetinal photodamage mediated by all-trans-retinal.Circadian and light-driven regulation of rod dark adaptation.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsNew therapeutic targets in atrophic age-related macular degeneration.A novel PRPF31 mutation in a large Chinese family with autosomal dominant retinitis pigmentosa and macular degeneration.Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle.A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.Biochemist strikes gold
P2860
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P2860
The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The specific binding of retino ...... tment of macular degeneration.
@ast
The specific binding of retino ...... tment of macular degeneration.
@en
type
label
The specific binding of retino ...... tment of macular degeneration.
@ast
The specific binding of retino ...... tment of macular degeneration.
@en
prefLabel
The specific binding of retino ...... tment of macular degeneration.
@ast
The specific binding of retino ...... tment of macular degeneration.
@en
P2860
P356
P1476
The specific binding of retino ...... tment of macular degeneration.
@en
P2093
Deviprasad R Gollapalli
Robert R Rando
P2860
P304
10030-10035
P356
10.1073/PNAS.0401936101
P407
P577
2004-06-24T00:00:00Z