The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).
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Recent advances in understanding the extracellular calcium-sensing receptorAutosomal Dominant Hypocalcemia (Hypoparathyroidism) Types 1 and 2Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasisTwo Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation.Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.Identification of a G-Protein Subunit-α11 Gain-of-Function Mutation, Val340Met, in a Family With Autosomal Dominant Hypocalcemia Type 2 (ADH2)Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors.Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy.Ways of calcium reabsorption in the kidney.Diseases associated with calcium-sensing receptorMutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy.Calcimimetic and calcilytic therapies for inherited disorders of the calcium-sensing receptor signalling pathway.Cinacalcet corrects hypercalcemia in mice with an inactivating Gα11 mutation.N-ethyl-N-nitrosourea-Induced Adaptor Protein 2 Sigma Subunit 1 (Ap2s1) Mutations Establish Ap2s1 Loss-of-Function Mice.The Different Facets of Extracellular Calcium Sensors: Old and New Concepts in Calcium-Sensing Receptor Signalling and Pharmacology.Extracellular calcium regulates protein tyrosine phosphorylation through calcium-sensing receptor (CaSR) in stallion sperm.Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma.
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P2860
The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@ast
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@en
type
label
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@ast
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@en
prefLabel
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@ast
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@en
P2093
P2860
P50
P356
P1433
P1476
The Calcilytic Agent NPS 2143 ...... nt Hypocalcemia Type 1 (ADH1).
@en
P2093
Allen M Spiegel
Gerard V Walls
Jianxin Hu
M Andrew Nesbit
Tertius A Hough
Valerie N Babinsky
William D Fraser
P2860
P304
P356
10.1210/EN.2015-1269
P407
P577
2015-06-08T00:00:00Z