PTPN22 alters the development of regulatory T cells in the thymus. - Wikidata - wikimedia - TriplyDB

PTPN22 alters the development of regulatory T cells in the thymus.

PTPN22 alters the development of regulatory T cells in the thymus.

http://www.wikidata.org/entity/Q35981147

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The role for protein tyrosine phosphatase non-receptor type 22 in regulating intestinal homeostasis Genetic Variations of PTPN2 and PTPN22: Role in the Pathogenesis of Type 1 Diabetes and Crohn's Disease Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity The thymus and rheumatology: should we care?The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human Advances in lupus genetics Genetics and epigenetics of rheumatoid arthritis Altered B cell homeostasis and toll-like receptor 9-driven response in type 1 diabetes carriers of the C1858T PTPN22 allelic variant: implications in the disease pathogenesis The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus PTPN22: the archetypal non-HLA autoimmunity gene.Genotype-Phenotype Associations of the CD-Associated Single Nucleotide Polymorphism within the Gene Locus Encoding Protein Tyrosine Phosphatase Non-Receptor Type 22 in Patients of the Swiss IBD Cohort Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.Association between PTPN22 C1858T polymorphism and alopecia areata risk Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes GWAS implicates a role for quantitative immune traits and threshold effects in risk for human autoimmune disorders PTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant.A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22 PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection.Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells Autologous regulatory T cells for the treatment of type 1 diabetes.Forkhead box P3: the peacekeeper of the immune system.Type 1 diabetes in mice and men: gene expression profiling to investigate disease pathogenesis.Functional dynamics of Foxp3⁺ regulatory T cells in mice and humans.Genetic aspects of anti-neutrophil cytoplasmic antibody-associated vasculitis.Ptpn22 Modifies Regulatory T Cell Homeostasis via GITR Upregulation.C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?PTPN22 and islet-specific autoimmunity: What have the mouse models taught us?Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis.Protein tyrosine phosphatase non-receptor type 22 gene polymorphism C1858T is not associated with leprosy in Azerbaijan, Northwest Iran.The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals.The molecular basis of immune regulation in autoimmunity.Regulation of autoimmune and anti-tumour T-cell responses by PTPN22.The rheumatoid arthritis susceptibility polymorphism PTPN22 C1858T is not associated with leflunomide response or toxicity.Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function.

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P2860

PTPN22 alters the development of regulatory T cells in the thymus.

http://www.wikidata.org/entity/Q35981147

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年论文

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name

PTPN22 alters the development of regulatory T cells in the thymus.

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PTPN22 alters the development of regulatory T cells in the thymus.

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PTPN22 alters the development of regulatory T cells in the thymus.

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PTPN22 alters the development of regulatory T cells in the thymus.

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PTPN22 alters the development of regulatory T cells in the thymus.

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PTPN22 alters the development of regulatory T cells in the thymus.

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JIMMUNOL.1200150

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Journal of Immunology

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PTPN22 alters the development of regulatory T cells in the thymus.

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Jocelyn Cheung

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Linda S Wicker

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Nunzio Bottini

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Stephanie M Stanford

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P2860

Identification of substrates of human protein-tyrosine phosphatase PTPN22

Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

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