Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice - Wikidata - wikimedia - TriplyDB

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

http://www.wikidata.org/entity/Q35983991

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Role of Cytokine-Induced Glycosylation Changes in Regulating Cell Interactions and Cell Signaling in Inflammatory Diseases and Cancer Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion The Goldilocks Conundrum: NLR Inflammasome Modulation of Gastrointestinal Inflammation during Inflammatory Bowel Disease Novel insights into microbiome in colitis and colorectal cancer.Loss of the mucosal barrier alters the progenitor cell niche via Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling.Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.A detection and quantification label-free tool to speed up downstream processing of model mucins.Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins.Polypeptide-GalNAc-T6 expression predicts better overall survival in patients with colon cancer.A molecular switch orchestrates enzyme specificity and secretory granule morphology The Dynamic Changes of Gut Microbiota in Deficient Mice Rhamnogalacturonan, a chemically-defined polysaccharide, improves intestinal barrier function in DSS-induced colitis in mice and human Caco-2 cells The Interaction of the Gut Microbiota with the Mucus Barrier in Health and Disease in Human

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P2860

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

http://www.wikidata.org/entity/Q35983991

description

2016 nî lūn-bûn

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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J.GASTRO.2016.03.039

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Gastroenterology

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Defective Intestinal Mucin-Typ ...... itis-Associated Cancer in Mice

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Christopher M West

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Courtney W Houchen

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Hong Chen

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J Michael McDaniel

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Kai Song

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Kirk Bergstrom

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Lijun Xia

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Mark M Huycke

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Nan Gao

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Qian Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

A genetic model for colorectal tumorigenesis

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

Non-canonical inflammasome activation targets caspase-11

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation.

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152-164.e11

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scholarly article

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10.1053/J.GASTRO.2016.03.039

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1

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Lauren A Zenewicz

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2016-04-06T00:00:00Z

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27059389

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