Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis.
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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretionAirway Gland Structure and FunctionIrbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in miceSubstance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process.Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigsMarked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel.Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approachCompartmentalized cyclic adenosine 3',5'-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains.Distribution and size of mucous glands in the ferret tracheobronchial tree.Mucus secretion from individual submucosal glands of the ferret trachea.Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs.CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotypePseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epitheliaProtease-activated receptor 2 mediates mucus secretion in the airway submucosal gland.Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters.In vivo readout of CFTR function: ratiometric measurement of CFTR-dependent secretion by individual, identifiable human sweat glandsSingle nucleotide polymorphisms in the 3'UTR of VPAC-1 cooperate in modulating gene expression and impact differently on the interaction with miR525-5p.Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins.Chloride secretion by cultures of pig tracheal gland cells.The porcine lung as a potential model for cystic fibrosisUpdate in cystic fibrosis 2007.Anion secretion by a model epithelium: more lessons from Calu-3.Autonomic neural control of intrathoracic airways.Vasoactive intestinal Peptide inhaled agonists: potential role in respiratory therapeuticsAirway and lung remodelling in chronic pulmonary obstructive disease: a role for muscarinic receptor antagonists?The gating of the CFTR channel.Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu-3.Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent.Cultures of human tracheal gland cells of mucous or serous phenotype.Introduction to section IV: biophysical methods to approach CFTR structure.CK2 is a key regulator of SLC4A2-mediated Cl-/HCO3- exchange in human airway epithelia.Why mouse airway submucosal gland serous cells do not secrete fluid in response to cAMP stimulation.CFTR Modulator Therapies in Pediatric Cystic Fibrosis: Focus on Ivacaftor.Carbachol-induced colonic mucus formation requires transport via NKCC1, K⁺ channels and CFTR.Transgenic animals may help resolve a sticky situation in cystic fibrosis.cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways.
P2860
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P2860
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@ast
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@en
type
label
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@ast
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@en
prefLabel
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@ast
Synergistic airway gland mucus ...... ol is lost in cystic fibrosis.
@en
P2093
P2860
P356
P1476
Synergistic airway gland mucus ...... hol is lost in cystic fibrosis
@en
P2093
Jeffrey J Wine
John W Hanrahan
Juan P Ianowski
Mauri E Krouse
Nam Soo Joo
Robert C Robbins
P2860
P304
P356
10.1172/JCI31992
P407
P577
2007-10-01T00:00:00Z