Comparative hybrid arrest by tandem antisense oligodeoxyribonucleotides or oligodeoxyribonucleoside methylphosphonates in a cell-free system
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Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analoguesPhysical properties of oligonucleotides containing phosphoramidate-modified internucleoside linkages.The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.Effect of a neutralized phosphate backbone on the minor groove of B-DNA: molecular dynamics simulation studies.Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism.Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages.Toward the therapeutic editing of mutated RNA sequences.Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotidesUncharged stereoregular nucleic acid analogs: 2. Morpholino nucleoside oligomers with carbamate internucleoside linkages.DNA and RNA derivatives to optimize distribution and deliveryEnhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation.Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistanceAntisense agents in cancer research and therapeutics.Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides.Evaluation of some properties of a phosphorodithioate oligodeoxyribonucleotide for antisense application.Targeting RNase L to human immunodeficiency virus RNA with 2-5A-antisense.Synthesis and physicochemical properties of oligonucleotides built with either alpha-L or beta-L nucleotides units and covalently linked to an acridine derivative.alpha-DNA X: alpha and beta tetrathymidilates covalently linked to oxazolopyridocarbazolium (OPC): comparative stabilization of oligo beta-[dT]:oligo beta-[dA] and oligo alpha-[dT]:oligo beta-[dA] duplexes by the intercalating agent.Oligonucleotide facilitators may inhibit or activate a hammerhead ribozymeDevelopment of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides: characterization of P(LA-GA) copolymer microspheres in vitro.Synthesis and thermodynamics of oligonucleotides containing chirally pure R(P) methylphosphonate linkages.Tat- and Rev-directed antisense RNA expression inhibits and abolishes replication of human immunodeficiency virus type 1: a temporal analysis.RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers.Facile preparation of nuclease resistant 3' modified oligodeoxynucleotides.Deprotection of methylphosphonate oligonucleotides using a novel one-pot procedure.Synthesis of oligodeoxynucleoside methylphosphonates utilizing the tert-butylphenoxyacetyl group for exocyclic amine protection.Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription.Sequence dependent effects in methylphosphonate deoxyribonucleotide double and triple helical complexes.Inhibition of human immunodeficiency virus (HIV-1) replication by synthetic oligo-RNA derivatives.Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: studies of An2 and cyclin in embryogenesis.Identification and analysis of antisense RNA target regions of the human immunodeficiency virus type 1.Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substratesRNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds.Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups.Two-component 10-23 DNA enzymes.
P2860
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P2860
Comparative hybrid arrest by tandem antisense oligodeoxyribonucleotides or oligodeoxyribonucleoside methylphosphonates in a cell-free system
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
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1988年學術文章
@zh-hant
name
Comparative hybrid arrest by t ...... phonates in a cell-free system
@ast
Comparative hybrid arrest by t ...... phonates in a cell-free system
@en
type
label
Comparative hybrid arrest by t ...... phonates in a cell-free system
@ast
Comparative hybrid arrest by t ...... phonates in a cell-free system
@en
prefLabel
Comparative hybrid arrest by t ...... phonates in a cell-free system
@ast
Comparative hybrid arrest by t ...... phonates in a cell-free system
@en
P2860
P356
P1476
Comparative hybrid arrest by t ...... phonates in a cell-free system
@en
P2093
Dolnick BJ
Maher LJ 3rd
P2860
P304
P356
10.1093/NAR/16.8.3341
P407
P577
1988-04-01T00:00:00Z