Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.
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Physical properties of oligonucleotides containing phosphoramidate-modified internucleoside linkages.Sequence-specific inhibition of gene expression by a novel antisense oligodeoxynucleotide phosphorothioate directed against a nonregulatory region of the human immunodeficiency virus type 1 genome.Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides.Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages.Making drugs out of oligonucleotides: a brief review and perspective.The use of antisense oligonucleotides in Xenopus oocytes.RNA therapeutics: beyond RNA interference and antisense oligonucleotides.Reversal of cystic fibrosis phenotype in a cultured Delta508 cystic fibrosis transmembrane conductance regulator cell line by oligonucleotide insertion.BCR-ABL as a target for novel therapeutic interventions.Site specific functionalization of oligonucleotides for attaching two different reporter groups.Triple-strand-forming methylphosphonate oligodeoxynucleotides targeted to mRNA efficiently block protein synthesis.Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: in vitro and in vivo studiesThe versatility of oligonucleotides as potential therapeutics.A brief history, status, and perspective of modified oligonucleotides for chemotherapeutic applications.Antimalarial activities of oligodeoxynucleotide phosphorothioates in chloroquine-resistant Plasmodium falciparum.Localization of pre-messenger RNA at discrete nuclear sites.Effects of RNA secondary structure on cellular antisense activity.Facilitating RNA structure prediction with microarraysAntisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidinesThe influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity.Mixed backbone antisense oligonucleotides: design, biochemical and biological properties of oligonucleotides containing 2'-5'-ribo- and 3'-5'-deoxyribonucleotide segments.Antisense oligonucleotide containing an internal, non-nucleotide-based linker promote site-specific cleavage of RNAMolecular requirements for degradation of a modified sense RNA strand by Escherichia coli ribonuclease H1Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modificationsSynthesis and thermodynamics of oligonucleotides containing chirally pure R(P) methylphosphonate linkages.Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells.Duplex stabilities of phosphorothioate, methylphosphonate, and RNA analogs of two DNA 14-mers.Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at near-physiological conditions.Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: studies of An2 and cyclin in embryogenesis.Gapmer Antisense Oligonucleotides Suppress the Mutant Allele of COL6A3 and Restore Functional Protein in Ullrich Muscular Dystrophy.Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor.Inhibition of zona pellucida gene expression by antisense oligonucleotides injected into mouse oocytes.Low U1 snRNP dependence at the NF1 exon 29 donor splice site.
P2860
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P2860
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@en
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@nl
type
label
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@en
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@nl
prefLabel
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@en
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@nl
P2093
P2860
P356
P1476
Site-specific excision from RN ...... ackbone oligodeoxynucleotides.
@en
P2093
P C Zamecnik
S H Mayrand
T Pederson
P2860
P304
P356
10.1073/PNAS.87.4.1401
P407
P577
1990-02-01T00:00:00Z