Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates
about
Biochemical properties of phosphonoacetate and thiophosphonoacetate oligodeoxyribonucleotidesPotential roles of antisense technology in cancer chemotherapy.Antisense agents in cancer research and therapeutics.Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.Effects of RNA secondary structure on cellular antisense activity.Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidinesHybridization properties of deoxyoligonucleotides containing anthraquinone pseudonucleosides.5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides.RNase H is responsible for the non-specific inhibition of in vitro translation by 2'-O-alkyl chimeric oligonucleotides: high affinity or selectivity, a dilemma to design antisense oligomers.Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells.Duplex stabilities of phosphorothioate, methylphosphonate, and RNA analogs of two DNA 14-mers.Biochemical properties of oligo [(+)-carbocyclic-thymidylates] and their complexes.The application of the AMB protective group in the solid-phase synthesis of methylphosphonate DNA analogues.Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: studies of An2 and cyclin in embryogenesis.Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.Evaluation of different types of end-capping modifications on the stability of oligonucleotides toward 3'- and 5'-exonucleases.
P2860
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P2860
Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Number and distribution of met ...... ity to form RNase H substrates
@en
type
label
Number and distribution of met ...... ity to form RNase H substrates
@en
prefLabel
Number and distribution of met ...... ity to form RNase H substrates
@en
P2093
P2860
P356
P1476
Number and distribution of met ...... ity to form RNase H substrates
@en
P2093
P2860
P304
P356
10.1093/NAR/17.18.7253
P577
1989-09-01T00:00:00Z