A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.
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The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MSImmunotherapy in autoimmune type 1 diabetesStructure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetesMolecular Interactions Governing Autoantigen Presentation in Type 1 DiabetesInsulin in human milk and the prevention of type 1 diabetesPro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cellsGenetics and pathogenesis of type 1 diabetes: prospects for prevention and interventionRecognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetopeSubcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma.Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitusTreg vaccination with a strong-agonistic insulin mimetope.Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection.Antigen-based vs. systemic immunomodulation in type 1 diabetes: the pros and cons.Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetesDivergent paths for the selection of immunodominant epitopes from distinct antigenic sources.TGF-beta signaling is required for the function of insulin-reactive T regulatory cellsZnT8-Specific CD4+ T cells display distinct cytokine expression profiles between type 1 diabetes patients and healthy adultsThe insulin gene in diabetes.Thymus-specific deletion of insulin induces autoimmune diabetes.Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells.GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23Tolerogenic vaccination reduced effector memory CD4 T cells and induced effector memory Treg cells for type I diabetes treatmentTreg vaccination in autoimmune type 1 diabetes.Cytokine detection by ELISPOT: relevance for immunological studies in type 1 diabetes.The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure.Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chainsRegulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.Type 1 diabetes: A predictable disease.Autoimmune diabetes: ongoing development of immunological intervention strategies targeted directly against autoreactive T cells"Persistence of Diabetes" - Why Has Research into Type 1 Diabetes not Made Significant Advances?Central and peripheral autoantigen presentation in immune tolerance.Telomere dysfunction, autoimmunity and aging.The Development and Application of HLA Tetramers in the Detection, Characterization and Therapy of Type 1 Diabetes Mellitus.Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.MAS-1 adjuvant immunotherapy generates robust Th2 type and regulatory immune responses providing long-term protection from diabetes in late-stage pre-diabetic NOD miceDistortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer PeptideEtiopathogenesis of insulin autoimmunity.
P2860
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P2860
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
A disease-associated cellular ...... nodominant epitope of insulin.
@ast
A disease-associated cellular ...... nodominant epitope of insulin.
@en
type
label
A disease-associated cellular ...... nodominant epitope of insulin.
@ast
A disease-associated cellular ...... nodominant epitope of insulin.
@en
prefLabel
A disease-associated cellular ...... nodominant epitope of insulin.
@ast
A disease-associated cellular ...... nodominant epitope of insulin.
@en
P2093
P2860
P356
P1476
A disease-associated cellular ...... nodominant epitope of insulin.
@en
P2093
Gottlieb PA
Gottschalk M
P2860
P304
P356
10.1172/JCI8525
P407
P577
2001-01-01T00:00:00Z