Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice.
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Chromogranin A is an autoantigen in type 1 diabetesImmunotherapy in autoimmune type 1 diabetesStructure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetesIntestinal parasitism terminates self tolerance and enhances neonatal induction of autoimmune disease and memory.Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)Antigen presentation pathways for immunity to islet transplants. Relevance to immunoisolation.Banting Lecture 2009: An unfinished journey: molecular pathogenesis to prevention of type 1A diabetes.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Gut and the induction of immune tolerance in type 1 diabetes.Gamma delta T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23.Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic miceRecognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.Extra-thymically induced regulatory T cells: do they have potential in disease prevention?The central role of antigen presentation in islets of Langerhans in autoimmune diabetesZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditionsAutoreactive CD8 T cells associated with beta cell destruction in type 1 diabetesTreg vaccination with a strong-agonistic insulin mimetope.Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetesA minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes.BDC12-4.1 T-cell receptor transgenic insulin-specific CD4 T cells are resistant to in vitro differentiation into functional Foxp3+ T regulatory cells.An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cellsEnvironmental factors in the etiology of type 1 diabetes.Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes.Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD miceTransfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.The role of T-cells in the pathogenesis of Type 1 diabetes: from cause to cure.Islet amyloid polypeptide is a target antigen for diabetogenic CD4+ T cells.Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chainsSpecificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.Development of new strategies to prevent type 1 diabetes: the role of animal models.Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletionProteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.Central and peripheral autoantigen presentation in immune tolerance.Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide
P2860
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P2860
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@ast
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@en
type
label
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@ast
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@en
prefLabel
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@ast
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@en
P2093
P356
P1476
Epitope specificity, cytokine ...... clones isolated from NOD mice.
@en
P2093
P304
P356
10.1002/EJI.1830250430
P407
P577
1995-04-01T00:00:00Z