Monoclonal antibody against the turn of the 42-residue amyloid β-protein at positions 22 and 23
about
Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues.Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer diseasePoint mutations in Aβ induce polymorphic aggregates at liquid/solid interfaces.Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.Development of new fusion proteins for visualizing amyloid-β oligomers in vivoMonoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer's disease diagnosis.The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β OligomersStructure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin.Formation of the 42-mer Amyloid β Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease.Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer's disease.Structural, morphological, and functional diversity of amyloid oligomers.Energetic contributions of residues to the formation of early amyloid-β oligomers.A Toxic Conformer of Aβ42 with a Turn at 22-23 is a Novel Therapeutic Target for Alzheimer's DiseaseE22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.Cytoplasmic superoxide radical: a possible contributing factor to intracellular Aβ oligomerization in Alzheimer disease.
P2860
Q30432271-5E6C41F4-F007-451F-9D7C-E8BDFEBAA1CFQ30534746-61E0298E-2DC0-43AD-9EB0-E107E535D117Q35639816-7D6CDD04-5AE1-49D5-8869-3378A036DB85Q36015441-2A3D869B-399E-4BA4-B131-509115EFCF59Q36248545-9CA194B5-9890-4D83-9A72-CBE8B2C23193Q36691716-12249B57-678A-4086-A51E-FEE0785D55C9Q37061562-1ED1AB94-C27E-4F34-8AD3-631682EC4C29Q37300268-23B9DECA-213E-4AD4-B80F-D279FC60A7E6Q37519267-09067FD1-6543-461B-B066-1A52681037F5Q37983824-0C951375-4057-40BB-8F8D-6373AD392ECFQ38240609-9133149A-B04F-4A66-B310-DF68B4C7B0F5Q38549882-7D1F1AC9-58B2-4CE3-9050-B8FE94B3EBE2Q39076914-E2C6064C-3EF0-46C7-97D5-527E36B27E45Q41717716-8CE1508D-791F-422B-ACD3-7B13760CE7C6Q41983258-CA338C24-A383-4D37-B0D7-5610967ECD39Q42276130-FA74132F-B7FC-4AEC-9DC8-DB0F41522C09
P2860
Monoclonal antibody against the turn of the 42-residue amyloid β-protein at positions 22 and 23
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Monoclonal antibody against th ...... protein at positions 22 and 23
@ast
Monoclonal antibody against th ...... protein at positions 22 and 23
@en
type
label
Monoclonal antibody against th ...... protein at positions 22 and 23
@ast
Monoclonal antibody against th ...... protein at positions 22 and 23
@en
prefLabel
Monoclonal antibody against th ...... protein at positions 22 and 23
@ast
Monoclonal antibody against th ...... protein at positions 22 and 23
@en
P2093
P2860
P356
P1476
Monoclonal antibody against th ...... protein at positions 22 and 23
@en
P2093
Hiroyuki Hatsuta
Kazuma Murakami
Nakaba Murata
Noriaki Kinoshita
Shigeo Murayama
Takahiko Shimizu
Takuji Shirasawa
Yuichi Masuda
Yuko Horikoshi-Sakuraba
P2860
P304
P356
10.1021/CN100072E
P577
2010-09-28T00:00:00Z