Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
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Genome-wide association analyses identify 18 new loci associated with serum urate concentrationsThe genetics of hyperuricaemia and goutUrate Handling in the Human BodyUric acid in metabolic syndrome: From an innocent bystander to a central playerCorrelation of GLUT9 Polymorphisms With Gout RiskRenal transport of uric acid: evolving concepts and uncertaintiesThe discovery of hypertension: evolving views on the role of the kidneys, and current hot topicsMendelian randomization: genetic anchors for causal inference in epidemiological studiesThe anatomical distribution of genetic associations.The organic anion transporter (OAT) family: a systems biology perspectiveExpression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variationsRedefining metabolic syndrome as a fat storage condition based on studies of comparative physiologySerum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approachTemporal disease trajectories condensed from population-wide registry data covering 6.2 million patientsMendelian Randomization as an Approach to Assess Causality Using Observational Data.Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association StudiesGenome-wide association of body fat distribution in African ancestry populations suggests new loci.Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.The frequency of single nucleotide polymorphisms and their association with uric acid concentration based on data from genome-wide association studies in the Korean population.The genetics of gout: towards personalised medicine?Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studiesReplication of Gout/Urate Concentrations GWAS Susceptibility Loci Associated with Gout in a Han Chinese Population.Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment optionsCausal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Sugar, uric acid, and the etiology of diabetes and obesity.The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease.Relationship between inflammatory cytokines and uric acid levels with adverse cardiovascular outcomes in patients with stable coronary heart disease.Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese populationReduced glomerular function and prevalence of gout: NHANES 2009-10An old disease with new insights: Update on diagnosis and treatment of gout.Gout: a review of nonmodifiable and modifiable risk factors.The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortalityThe reduction of vascular disease risk mutations contributes to longevity in the Chinese population.Associations of the uric acid related genetic variants in SLC2A9 and ABCG2 loci with coronary heart disease risk.Evidence of gene-environment interaction for two genes on chromosome 4 and environmental tobacco smoke in controlling the risk of nonsyndromic cleft palate.Modulation of genetic associations with serum urate levels by body-mass-index in humansSerum uric acid concentrations and SLC2A9 genetic variation in Hispanic children: the Viva La Familia StudyAn update on the genetic architecture of hyperuricemia and goutA comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees.The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity
P2860
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P2860
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Multiple genetic loci influenc ...... vascular disease risk factors.
@ast
Multiple genetic loci influenc ...... vascular disease risk factors.
@en
type
label
Multiple genetic loci influenc ...... vascular disease risk factors.
@ast
Multiple genetic loci influenc ...... vascular disease risk factors.
@en
prefLabel
Multiple genetic loci influenc ...... vascular disease risk factors.
@ast
Multiple genetic loci influenc ...... vascular disease risk factors.
@en
P2093
P2860
P50
P1476
Multiple genetic loci influenc ...... vascular disease risk factors.
@en
P2093
Alex N Parker
Bruno Stricker
Caroline S Fox
Christopher J O'Donnell
Dan E Arking
Daniel I Chasman
Dena Hernandez
Jacqueline C Witteman
Megan L Grove
P2860
P304
P356
10.1161/CIRCGENETICS.109.934455
P50
P577
2010-09-30T00:00:00Z