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Nuclear Tau and Its Potential Role in Alzheimer's DiseaseAlzheimer's Disease: Mechanism and Approach to Cell TherapyConnecting the dots between tau dysfunction and neurodegenerationMicrotubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with agingPTL-1 regulates neuronal integrity and lifespan in C. elegans.A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditionsStructure and mechanism of action of tau aggregation inhibitors.No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin MiceMechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effectsRemoving endogenous tau does not prevent tau propagation yet reduces its neurotoxicityAbsence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairmentDeletion of endogenous Tau proteins is not detrimental in Drosophila.Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase.What Renders TAU ToxicImpaired burrowing is the most prominent behavioral deficit of aging htau mice.Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes.The evolution and diversification of plant microtubule-associated proteins.Microtubule dynamics in axon guidance.Stability properties of neuronal microtubules.Tau Positron Emission Tomography Imaging.Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs.Neurodegenerative Disease Transmission and Transgenesis in Mice.Tau exacerbates excitotoxic brain damage in an animal model of stroke.Loss of Tau results in defects in photoreceptor development and progressive neuronal degeneration in Drosophila.Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology.Synthesis and selective 2 H-, 13 C-, and 15 N-labeling of the Tau protein binder THK-523.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
Lessons from tau-deficient mice
@ast
Lessons from tau-deficient mice
@en
type
label
Lessons from tau-deficient mice
@ast
Lessons from tau-deficient mice
@en
prefLabel
Lessons from tau-deficient mice
@ast
Lessons from tau-deficient mice
@en
P2093
P2860
P356
P1476
Lessons from tau-deficient mice
@en
P2093
Alexandra K Suchowerska
Christopher W Wu
Dineeka M De Silva
Janet van Eersel
Julia van der Hoven
P2860
P304
P356
10.1155/2012/873270
P577
2012-06-06T00:00:00Z