Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.
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Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cellsPancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stressThe B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKRLatently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase.Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKRThe 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteinsExpression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growthNucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKRPACT, a protein activator of the interferon-induced protein kinase, PKR.Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPKIdentification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational controlA new double-stranded RNA-binding protein that interacts with PKROncogenic role of Epstein-Barr virus-encoded RNAs in Burkitt's lymphoma cell line AkataPhysical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathwaysThe C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alphaAntiviral actions of interferonsA herpesvirus genetic element which affects translation in the absence of the viral GADD34 functionTranslational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinaseDouble-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivoA dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferonPrecursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity.Cytoplasmic p53 polypeptide is associated with ribosomesbic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNAAutophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKRRAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infectionImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionThe modulation of apoptosis by oncogenic virusesControl of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation.Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesisAntiapoptotic and oncogenic potentials of hepatitis C virus are linked to interferon resistance by viral repression of the PKR protein kinaseHistidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2.Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control.RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signalingThe double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitroTwo dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expressionNuclear factor 90 is a substrate and regulator of the eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinaseThe direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation
P2860
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P2860
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Tumor suppressor function of t ...... RNA-activated protein kinase.
@ast
Tumor suppressor function of t ...... RNA-activated protein kinase.
@en
type
label
Tumor suppressor function of t ...... RNA-activated protein kinase.
@ast
Tumor suppressor function of t ...... RNA-activated protein kinase.
@en
prefLabel
Tumor suppressor function of t ...... RNA-activated protein kinase.
@ast
Tumor suppressor function of t ...... RNA-activated protein kinase.
@en
P2093
P2860
P356
P1476
Tumor suppressor function of t ...... RNA-activated protein kinase.
@en
P2093
A G Hovanessian
G N Barber
P2860
P304
P356
10.1073/PNAS.90.1.232
P407
P577
1993-01-01T00:00:00Z